Stem cell therapy: a promising frontier in modern medicine with a comprehensive overview of their biology and potential therapeutic applications in chronic non-healing cutaneous injuries.

Chronic wounds represent significant challenges to the healthcare system. Their incidence increases with increase in age, especially in individuals suffering from chronic disorders like diabetes. The process of wound healing consists of a series of coordinated biological events triggered by tissue damage, ultimately leading to the repair and restoration of damaged tissues.

Distachionate and Its Nanocomposites Modulate Oxidative Stress, Inflammation, and Diabetes-Related Genes in High-Fructose/Streptozotocin Model.

Medicinal plants, known for their bioactive compounds, have long been utilized for the treatment of various diseases, including diabetes. A novel compound, distachionate (DST), was isolated as a yellowish powder from , referred to as snowbush. It is known to possess pronounced antioxidant and anti-inflammatory activities mediated through the modulation of COX-2 and inflammatory cytokines.

Antidiabetic activity of is possibly mediated through modulation of insulin signaling pathway, inflammatory cytokines and adipocytokines in high fat diet and streptozotocin-administered rats.

Medicinal plants play a key role in protection of chronic non-communicable ailments like diabetes, hypertension and dyslipidemia. Ahrendt (Berberidaceae) is traditionally used to treat diabetes, liver problems, wounds, arthritis, infections, swelling and tumors. It is also known to be enriched with multiple phytoconstituents including berbamine, berberine, quercetin, gallic acid, caffeic acid, vanillic acid, benzoic acid, chlorogenic acid, syringic acid, -coumaric acid, -coumaric acid and ferulic acid.

and its metabolite coumarin attenuate characteristic features of cardiometabolic syndrome in high-refined carbohydrate-high fat-cholesterol-loaded feed-fed diet rats.

(D. Don) B.L.