Pembrolizumab-Induced Thyroid Storm in a Patient With Triple-Negative Breast Cancer.

Background/objective: Thyroid immune-related adverse events (irAEs) are a common occurrence with the use of anti-programmed cell death-1 agents such as pembrolizumab. Anti-programmed cell death-1-induced thyroid storm in the absence of autoimmune thyroid disease is a rare but potentially fatal complication. This report aims to highlight the varied spectrum of thyroid irAEs, emphasize the importance of early detection, and discuss the challenges involved in diagnosing and managing these conditions.

A Rare Case of Tumor-to-Tumor Metastasis: Renal Cell Carcinoma Metastasis to Papillary Thyroid Carcinoma.

Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy. Renal cell carcinoma (RCC) metastasis to the thyroid, albeit the most common carcinomatous metastasis to the thyroid, is rare, and tumor-to-tumor metastasis of RCC to PTC is even rarer. We present a case of a 65-year-old male with a history of RCC who presented with a thyroid nodule 7 years after left radical nephrectomy.

Obesity-Induced Hyperglycemia and Heart Failure Preserved Ejection Fraction: Uncharted Territories to Remission.

Until the end of World War II, food security was a global challenge. Consequently, in 1948, type 2 diabetes was relatively uncommon, with the majority of cases being type 1 diabetes requiring insulin therapy. Since then, food has become increasingly palatable and readily available, leading to a rise in obesity across all age groups.

Thyrotoxic Periodic Paralysis as an Ongoing Diagnostic Challenge: A Case Report and Literature Review.

Thyrotoxic periodic paralysis (TPP) is a rare condition that presents with episodic periodic paralysis due to hypokalemia that develops from hyperthyroidism. Timely diagnosis is still an ongoing challenge due to lack of awareness, self-resolving episodes, and the fact that it clinically mimics familial hypokalemic periodic paralysis (FHPP), which is more common in the West. TPP is more commonly seen among Asians but has been emerging in Western countries due to globalization.

Impact of Marital Status on Tumor Stage at Diagnosis and on Survival in Male Breast Cancer.

The effect of marital status (MS) on survival varies according to cancer type and gender. There has been no report on the impact of MS on survival in male breast cancer (MBC). This study aims to determine the influence of MS on tumor stage at diagnosis and survival in MBC.