Emergency below-knee amputation (BKA) in patients with significant comorbidities and coagulopathy presents formidable anesthetic challenges, as a central neuraxial blockade and general anesthesia are frequently contraindicated. We report the case of a 57-year-old female patient with uncontrolled diabetes mellitus, chronic kidney disease, coronary artery disease, and an elevated international normalized ratio (INR) of 1.6, necessitating urgent BKA for a septic diabetic foot ulcer.
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