Publications by authors named "Sharon R Ha"
The energetic brain - A review from students to students.
Melina Paula Bordone
,
Mootaz M Salman
,
Haley E Titus
,
Elham Amini
,
Jens V Andersen
,
Barnali Chakraborti
,
Richa Gupta
,
Sharon R Ha
,
Sorabh Sharma
,
Kunjbihari Sulakhiya
,
Anuradha Yadav
J Neurochem
October 2019
Article Synopsis
- Over the past two decades, there's been significant progress in understanding how the brain's energy metabolism impacts health and disease, particularly due to its high energy demands from numerous neurons and essential functions.
- Disruptions in energy balance, mitochondrial control, or glia-neuron interactions can lead to brain circuit issues or serious central nervous system disorders.
- The review also covers key energy sources like glucose, glutamate, lactate, ketones, and how non-neuronal cells like astrocytes play crucial roles in energy transport and supply in the brain.
The site of action potential initiation in sensory neurons remains poorly understood. In this issue of Neuron, Goldstein et al. (2019) identified the location of the sodium-dependent spike initiation zone (Nav-SIZ) in nociceptive neurons, showing its plasticity under inflammatory conditions.
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