Risk of nonunion for dual plate versus single plate fixation for humeral shaft and distal humerus fractures: a systematic review and meta-analysis.

Objective: This study's purpose was to compare clinical outcomes in adult patients who underwent dual plate versus single plate fixation for humerus fractures to enhance decision-making and patient care.

Methods: Data sources: A pre-registered systematic review and meta-analysis searched four databases on January 9th, 2025. Inclusion criteria were studies that compared dual versus single plate fixation for humerus fractures.

Is postoperative ketorolac administration associated with nonunion in adults after proximal humerus open reduction and internal fixation? a propensity-matched retrospective cohort study.

Introduction: Although ketorolac's association with poor bone healing remains debated, no study has examined the impact of ketorolac administration in adults with proximal humerus fractures (PHFs) after open reduction and internal fixation (ORIF), limiting surgeon decision-making. Therefore, the primary aim of this study was to examine the association between short-term ketorolac administration within the first three days after ORIF for PHF and the incidence and risk of nonunion or malunion through one year.

Methods: A pre-registered retrospective propensity-matched cohort study was performed using a large United States health records-based database (TriNetX, LLC).

Risk of venous thromboembolism and bleeding complications for early enoxaparin versus heparin after same-day spine surgery for central cord syndrome: A propensity-matched retrospective cohort study.

Study Design: Retrospective cohort study.

Objective: The primary purpose of this study is to compare the effect of enoxaparin versus heparin on the risk of venous thromboembolism (VTE) after early spine surgery for CCS, hypothesizing no difference in risk.

Setting: Multi-site academic centers.

Is osteoporosis an independent risk factor for sacral fracture after lumbosacral spinal fusion in adults? A retrospective cohort study.

Background Context: Sacral fracture is a rare complication following lumbosacral fusion in adults linked to postsurgical biomechanical changes. There are mixed research results suggesting that osteoporosis may or may not be a contributing factor.

Purpose: To determine if osteoporosis is an independent risk factor for sacral fracture after lumbosacral fusion.