Publications by authors named "Shackelford S"

The article provides a detailed description of a case of combat injury in Ukraine due to a bullet wound to the neck involving intravascular migration of the bullet through major veins into the right atrium. Surgical care was provided at a role 3 hospital in eastern Ukraine. The authors emphasize the differences in the clinical picture and surgical treatment of a patient with migration of a foreign body to the heart compared to traumatic cardiac injury.

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Background: Large-scale combat operations (LSCO) generate high casualty volumes, challenging battlefield trauma care and necessitating a synchronized approach that integrates medical operations with warfighting functions. Existing casualty management tools, such as the Medical Planners Toolkit and Joint Medical Planning Tool, provide static estimates and lack predictive capabilities for evacuation and medical resupply. The Automated Battlefield Trauma System (ABTS) was developed to address these limitations by automating casualty categorization, resource estimation, and Medical Common Operating Picture reporting.

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Heterosis, or hybrid vigor, is traditionally defined as the advantage of crossbred progeny relative to the average performance of their purebred parents. This advantage is due to increased heterozygosity in these crosses, which increases phenotypic expression in traits influenced by non-additive gene action. These heterosis effects may vary depending on the breed of animals in the original cross; however, breed-specific estimates are difficult to obtain because of a lack of contemporary comparisons among crossbred and purebred cattle.

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Herein, we present a simplified approach to prehospital mass casualty event (MASCAL) management called "Move, Treat, and Transport." Prior publications demonstrate a disconnect between MASCAL response training and actions taken during real-world incidents. Overly complex algorithms, infrequent training on their use, and chaotic events all contribute to the low utilization of formal triage systems in the real world.

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Introduction: Emergency resuscitative thoracotomy (ERT) is a resource-intensive procedure that can deplete a combat surgical team's supply and divert attention from casualties with more survivable injuries. An understanding of survival after ERT in the combat trauma population will inform surgical decision-making.

Methods: We requested all encounters from 2007 to 2023 from the Department of Defense Trauma Registry (DoDTR).

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Introduction: Mass casualty events (MASCALs) in the combat environment, which involve large numbers of casualties that overwhelm immediately available resources, are fundamentally chaotic and dynamic and inherently dangerous. Formal triage systems use diagnostic algorithms, colored markers, and four or more named categories. We hypothesized that formal triage systems are inadequately trained and practiced and too complex to successfully implement in true MASCAL events.

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Background: Damage-control resuscitation has come full circle, with the use of whole blood and balanced components. Lack of platelet availability may limit effective damage-control resuscitation. Platelets are typically stored and transfused at room temperature and have a short shelf-life, while cold-stored platelets (CSPs) have the advantage of a longer shelf-life.

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Background: Extremity tourniquets have proven to be lifesaving in both civilian and military settings and should continue to be used by first responders for trauma patients with life-threatening extremity bleeding. This is especially true in combat scenarios in which both the casualty and the first responder may be confronted by the imminent threat of death from hostile fire as the extremity hemorrhage is being treated. Not every extremity wound, however, needs a tourniquet.

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Article Synopsis
  • The study reviews US military fatalities from combat trauma between 2001 and 2021 to identify potential survival-benefitting interventions and improve trauma care systems.
  • Out of 388 fatalities analyzed, 100 were identified as potentially survivable, with the majority occurring prehospital and involving severe injuries such as gunshot wounds.
  • A panel of medical experts recommended 433 interventions, highlighting blood transfusion as the most critical prehospital intervention and thoracotomy as vital in hospital settings for improving survival outcomes.
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Battlefield lessons learned are forgotten; the current name for this is the Walker Dip. Blood transfusion and the need for a Department of Defense Blood Program are lessons that have cycled through being learned during wartime, forgotten, and then relearned during the next war. The military will always need a blood program to support combat and contingency operations.

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Article Synopsis
  • Aggregate statistics help compare mortality rates in U.S. combat operations, but individual-level data on factors affecting casualty mortality has been hard to gather historically.* -
  • The DoD Trauma Registry provides valuable individual-level data from conflicts in Afghanistan and Iraq, allowing for detailed analyses of factors influencing combat casualty outcomes.* -
  • To better understand combat fatalities and improve survival rates, the commentary suggests integrating data from the Trauma Mortality Review with traditional aggregate statistics, focusing on prevention strategies for injuries.*
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Background: Clinicians working in intensive care units (ICUs) are immersed in a cacophony of alarms and a relentless onslaught of data. Within this frenetic environment, clinicians make high-stakes decisions using many data sources and are often oversaturated with information of varying quality. Traditional bedside monitors only depict static vital signs data, and these data are not easily viewable remotely.

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We have highlighted the issue of overuse of tourniquets and described why tourniquet conversion and replacement should be taught and done in the prehospital setting.

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Background: Combat-related gunshot wounds (GSW) may differ from those found in civilian trauma centers. Missile velocity, resources, logistics, and body armor may affect injury patterns and management strategies. This study compares injury patterns, management, and outcomes in isolated abdominal GSW between military (MIL) and civilian (CIV) populations.

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Analysis and review of combat casualty care challenges in future large-scale and medical multi-domain operations from the perspective of past, present, and potential future conflicts.

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Introduction: Colon and rectal injuries have been diverted at higher rates in military trauma compared with civilian injuries. However, in the last few years, there has been a shift to more liberal primary anastomosis in wartime injuries. The purpose of this study was to compare the management and outcomes in colorectal gunshot wounds (GSWs) between military and civilian settings.

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Introduction: In recent conflicts, the Joint Theater Trauma System (JTTS) led the systematic approach to improve battlefield trauma care, substantially contributing to the unprecedented survival of combat casualties. The Joint Trauma System (JTS) was codified in 2016 to preserve the lessons learned and functions of the JTTS, including the Department of Defense Trauma Registry. Concurrently, Combatant Commands (CCMD) were directed to establish CCMD Trauma Systems (CTS) "modeled after the JTTS" and to maintain a baseline of core functions intended to rapidly scale as needed.

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Objective: To examine time from injury to initiation of surgical care and association with survival in US military casualties.

Background: Although the advantage of trauma care within the "golden hour" after an injury is generally accepted, evidence is scarce.

Methods: This retrospective, population-based cohort study included US military casualties injured in Afghanistan and Iraq, January 2007 to December 2015, alive at initial request for evacuation with maximum abbreviated injury scale scores ≥2 and documented 30-day survival status after injury.

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Major trauma frequently occurs in the deployed, combat setting and is especially applicable in the recent conflicts with explosives dominating the combat wounded. In future near-peer conflicts, we will likely face even more profound weapons including mortars and artillery. As such, the number of severely wounded will likely increase.

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Introduction: Falls are a leading mechanism of injury. Hospitalization and outpatient clinic visits due to fall injury are frequently reported among both deployed and non-deployed U.S.

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Mitochondrial DNA copy number (mtDNA CN) is heritable and easily obtained from low-pass sequencing (LPS). This study investigated the genetic correlation of mtDNA CN with growth and carcass traits in a multi-breed and crossbred beef cattle population. Blood, leucocyte, and semen samples were obtained from 2,371 animals and subjected to LPS that resulted in nuclear DNA (nuDNA) and mtDNA sequence reads.

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Penetrating traumatic brain injury (pTBI) affects civilian and military populations resulting in significant morbidity, mortality, and healthcare costs. No up-to-date and evidence-based guidelines exist to assist modern medical and surgical management of these complex injuries. A preliminary literature search revealed a need for updated guidelines, supported by the Brain Trauma Foundation.

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Consumer interest in grass-fed beef has been steadily rising due to consumer perception of its potential benefits. This interest has led to a growing demand for niche market beef, particularly in the western United States. Therefore, the objective of this study was to assess the impact of feeding systems on the change in microbial counts, color, and lipid oxidation of steaks during retail display, and on their sensory attributes.

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Objective: The purpose of this study was to compare therapeutic strategies and outcomes, following isolated gunshot wounds of the head, between military and civilian populations.

Background: Recent military conflicts introduced new concepts in trauma care, including aggressive surgical intervention in severe head trauma.

Methods: This was a cohort-matched study, using the civilian Trauma Quality Improvement Program (TQIP) database of the American College of Surgeons (ACS) and the Department of Defense Trauma Registry (DoDTR), during the period 2013 to 2016.

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