Publications by authors named "Andrew D Fisher"

Introduction: Acute traumatic coagulopathy remains a high predictor of mortality; however, the incidence and outcomes in the military population have limited data. The goal of our study is to characterize coagulopathy on arrival to deployed Role 2 and Role 3 Military Treatment Facilities (MTFs).

Materials And Methods: We utilized the Department of Defense Trauma Registry to identify United States (U.

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Background: Deploying surgeons frequently train, prepare, and bring equipment to manage adult trauma patients without sufficient planning and consideration for pediatric trauma populations. Pediatric urotrauma in this setting requires specialty care as part of the humanitarian mission. We determine the incidence of genitourinary trauma and relevant surgical procedures within the pediatric population seen in US military treatment facilities in Afghanistan and Iraq from January 2007 to January 2016.

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Background: Emergency front of neck access (eFONA) is an emergent procedure performed in "cannot intubate, cannot ventilate" scenarios to establish a patent airway that was otherwise compromised. We sought to describe the recent literature on eFONA.

Methods: We conducted a scoping review using the PRISMA-ScR Checklist to provide comprehensive summary of the most relevant eFONA literature over topics such as civilian and military incidence and outcome, available techniques, the use of ultrasound in performing eFONA, training data, complications and contraindications, and emerging data on the procedure.

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Hemorrhagic shock remains the leading cause of potentially preventable death among injured patients with life-threatening bleeding. Prehospital resuscitation has been evolving with increasing use of blood product resuscitation. The impact of blood administration on patient outcomes remains poorly defined with significant heterogeneity in the quality of literature supporting prehospital blood product resuscitation after trauma.

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Introduction: Hemorrhage is the leading cause of death after trauma. Blood transfusions are used to restore physiology but are stored in citrate preservative which can bind electrolytes, particularly calcium, leading to hypocalcemia. Few data exist on the changes that occur in humans because of whole blood donation/transfusion.

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Introduction: Data on the correlation between transfusion volumes and trauma mortality are limited. The association between the total number of red blood cell (RBC) and low titer group O whole blood (LTOWB) units, as well as the total volume of all transfused products that were administered up to 4-h after admission and 24-h mortality was determined.

Methods: The Trauma Quality Improvement Program (TQIP) datasets from 2020 to 2022 were reviewed to identify patients aged ≥15 who received any volume of blood products.

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Introduction: Transfusion of whole blood (WB) for traumatic hemorrhage has generated renewed interest in civilian trauma based on military experience. The association between blood products and severe sepsis remains unknown. We sought to determine which blood products were associated with the development of severe sepsis.

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Introduction: Trauma care frequently happens in emergency departments (ED) outside of major trauma centers. Many injuries often exceed the specialty capabilities of referring hospitals, requiring transfer to larger trauma centers. However, the proportion of patients discharged home without admission from receiving facilities remains unclear, suggesting potential overutilization of transfers.

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Introduction: Hemorrhage is a leading cause of death in pediatric patients. Accumulating data suggest that low-titer group O whole blood (LTOWB) improves clinical outcomes in the pediatric population. We examined what ratio of LTOWB to total blood product conferred a survival benefit in transfused pediatric trauma patients.

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Objectives: To determine the association of whole blood and other blood products (components, prothrombin complex concentrate, and fibrinogen concentrate) with the development of acute respiratory distress syndrome (ARDS) among blood recipients.

Design: Retrospective cohort study.

Setting: American College of Surgeons Trauma Quality Improvement Program (TQIP) database between 2020 and 2021.

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Background: Junctional hemorrhage is a leading cause of battlefield death. Multiple FDA-approved junctional tourniquet (JTQ) models demonstrate effective hemorrhage control in laboratory settings. However, there are few real-world use cases within the literature.

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Objectives: Studies comparing police, privately owned vehicle (POV), and ground Emergency Medical Services (GEMS) trauma transports reveal mixed results. It remains unclear whether using nonstandard transport methods may be beneficial in the setting of certain injuries. We sought to determine 24-h survival after transport by police or POV when compared to GEMS.

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Article Synopsis
  • The study investigates calcium imbalances in soldiers injured during combat, focusing on their occurrence in emergency departments and their relation to other health issues and mortality within 24 hours.
  • Out of 941 military casualties, 26% exhibited calcium abnormalities, with hypocalcemia being more common (22%) than hypercalcemia (5%).
  • Patients with calcium derangements had lower injury severity scores and a higher survival rate in the hospital compared to those without derangements, although 24-hour survival rates were similar.
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Article Synopsis
  • Airway management is crucial for critically ill trauma patients, and the study examines the use of emergency surgical airway (ESA) as a backup method when endotracheal intubation (ETI) fails.
  • The research analyzed data from 2017 to 2022, finding that out of over 6 million cases, 2264 ESAs were performed, primarily in patients with more severe injuries, especially to the head/neck and face.
  • The study showed higher survival rates for ETI-only patients over those who received an ESA, and specific types of injuries (like firearms and stabbings) increased the likelihood of needing an ESA.
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Introduction: Emergency resuscitative thoracotomy (ERT) is a resource-intensive procedure that can deplete a combat surgical team's supply and divert attention from casualties with more survivable injuries. An understanding of survival after ERT in the combat trauma population will inform surgical decision-making.

Methods: We requested all encounters from 2007 to 2023 from the Department of Defense Trauma Registry (DoDTR).

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Article Synopsis
  • A study investigated the use of resuscitative endovascular balloon occlusion of the aorta (REBOA) for managing severe torso trauma in emergency departments, highlighting its controversial role and limited data on patient outcomes.
  • The analysis included 3,398 REBOA procedures from 2017 to 2022, mostly involving male patients with an average age of 40, primarily stemming from collision injuries.
  • The findings showed that while survival rates were high (85%) shortly after REBOA placement, they declined significantly to 42% by discharge, indicating room for improvement in patient selection and outcomes.
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Article Synopsis
  • Hemorrhage is a major cause of death, and blood products, particularly low titer group O whole blood (LTOWB), are increasingly used to treat patients with hemorrhagic shock.
  • A study analyzed data from over 12,000 trauma patients, finding that 30% received LTOWB within the first 4 hours after hospital arrival.
  • Results indicated that while LTOWB did not show a survival difference at 6 hours, patients receiving at least 10% of LTOWB relative to total blood products had a higher chance of surviving for 24 hours.
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Background: The risks associated with blood product administration and venous thromboembolic events remains unclear. We sought to determine which blood products were associated with the development of deep vein thrombosis (DVT) and pulmonary embolism (PE).

Methods: We analyzed data from patients ≥18 years of age in the Trauma Quality Improvement Program (TQIP) database that received ≥1 blood product and survived ≥24 ​h.

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Introduction: Blood transfusions are common during combat casualty care, aiming to address the loss of blood volume that often accompanies severe battlefield injuries. This scoping review delves into the existing military combat casualty data to analyze the efficacy, challenges, and advances in the use of massive and super-massive transfusions in the management of critically injured warfighters.

Materials And Methods: We performed a scoping review of combat-related literature published between 2006 and 2023 pertaining to massive transfusions used during combat deployments.

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Background: Damage-control resuscitation has come full circle, with the use of whole blood and balanced components. Lack of platelet availability may limit effective damage-control resuscitation. Platelets are typically stored and transfused at room temperature and have a short shelf-life, while cold-stored platelets (CSPs) have the advantage of a longer shelf-life.

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Background: Thoracic trauma occurs frequently in combat and is associated with high mortality. Tube thoracostomy (chest tube) is the treatment for pneumothorax resulting from thoracic trauma, but little data exist to characterize combat casualties undergoing this intervention. We sought to describe the incidence of these injuries and procedures to inform training and materiel development priorities.

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Background: The development of acute traumatic coagulopathy is associated with increased mortality and morbidity in patients with battlefield traumatic injuries. Currently, the incidence of acute traumatic coagulopathy in the Role 1 setting is unclear.

Methods: We queried the Prehospital Trauma Registry (PHTR) module of the Department of Defense Trauma Registry (DoDTR) for all encounters from inception through May 2019.

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