Publications by authors named "Shabana Andleeb Ansari"

Pediatric spindle cell tumors are rare tumors involving head and neck region. The histology of this type of tumor varies from benign to malignant. Immunohistochemical markers (IHC) help in differentiating and grading of tumor.

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Introduction: Cervical cancer screening using Pap smears is affected by false-negative results. Liquid-based cytology (LBC) offers the technical advantage of preparing cell blocks from residual fluid to conduct ancillary tests on them. The p16INK4a gene product has been shown to be strongly overexpressed in dysplastic cervical epithelia and serves as surrogate marker for high-risk human papilloma virus infection.

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Laboratory tests have been used as prognostic markers in various diseases, especially those with infectious etiology, but the information on the role of biochemical parameters in the risk assessment of patients with COVID-19 is limited. We designed this retrospective cohort study to investigate the utility of troponin-I in predicting the in-hospital mortality of patients with COVID-19 admitted to our tertiary care hospital in central India. We strategically recorded the history, findings on physical examination, comorbid conditions, clinical diagnosis, results of the biochemical parameters, and adverse outcomes (in terms of survival or death) in order to assess the utility of troponin-I estimation done within the first 24 hours of admission in predicting the in-hospital mortality of patients with COVID-19.

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Article Synopsis
  • This study examines how biochemical factors can help predict what kind of ventilatory support severely ill COVID-19 patients might need, as previous research has mainly focused on mortality predictions.
  • The research found significant differences in various biochemical levels between patients on non-invasive versus invasive ventilation, noting that higher levels of Urea, Sodium, Indirect Bilirubin, AST, and Procalcitonin are associated with the need for invasive support, while lower Albumin levels are linked to this requirement.
  • The results suggest that monitoring these biochemical parameters could improve patient management in ICUs by helping determine which type of ventilation might be most suitable for individual patients.
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Background Prognostication plays a pivotal role in critical care medicine. Its importance is indisputable in the management of coronavirus disease 2019 (COVID-19), as the presentation of this disease may vary from docile, self-limiting symptoms to lethal conditions. Amid the COVID-19 pandemic, much emphasis was initially placed on molecular and serological testing.

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