NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease.

Alzheimer's disease (AD) associates closely associated with the activation of NADPH oxidase (Nox) isozymes. CRB-2131, a novel oxadiazole derivative, is identified as a potently suppresses Nox isozymes. It inhibits reactive oxygen species production (ROS) by hippocampal neuronal and microglial cells and reduces microglial activation.

Surface modifications by wet oxidation method removing getter layer in crystalline silicon cells.

Reducing the impurity atom content in crystalline silicon (c-Si) can effectively reduce the recombination current density ( ) and improve the photoelectric conversion efficiency (PCE) of solar cells. Phosphorus diffusion gettering (PDG) has been proven to be an effective method to remove impurity atoms from c-Si. However, the research studies show that the traditional tube thermal diffusion method will cause a large number of dislocations on the silicon surface during the oxidation process, reducing the effectiveness of gettering.