Circulating Epstein-Barr virus DNA and cell-free DNA in pediatric lymphomas.

Background And Objectives: Quantification of serum Epstein-Barr virus (EBV) DNA and/or cell-free total DNA (cf-DNA) may become valuable sources for prognosis evaluation and monitoring treatment response in lymphomas. We aimed to investigate their roles as potential markers in pediatric Hodgkin (HL) and non- Hodgkin lymphomas (NHL).

Method: Between the years 2005-2008, 34 patients with HL and 45 with NHL were prospectively included.