Publications by authors named "Sefora Fischetti"
: This study aims to distinguish radiological differences between primary idiopathic Usual Interstitial Pneumonia (UIP) and secondary UIP patterns : This retrospective study included patients with HRCT findings consistent with a UIP pattern. Final diagnoses were established via multidisciplinary discussion and classified as primary UIP/IPF or secondary UIP, following the 2022 ATS/ERS/JRS/ALAT guidelines. An expert thoracic radiologist (>10 years of experience), blinded to clinical data, reviewed the earliest available HRCT assessing key imaging features: honeycombing (micro-, macro- or exuberant), fibrosis distribution (symmetry, anterior-upper lobe sign, etc.
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- - The study introduces "UIPAF," a term for patients with Usual Interstitial Pneumonia linked only to one aspect of "Interstitial Pneumonia with Autoimmune Features," aiming to compare its clinical outcomes with IPAF and idiopathic pulmonary fibrosis (IPF) patients.
- - A total of 110 IPF, 69 UIPAF, and 123 IPAF patients were analyzed, showing that UIPAF patients have autoimmune traits similar to IPAF but differ in certain antibody presence, with both groups having a similar rate of progression to specific autoimmune diseases.
- - Findings indicate that UIPAF shares autoimmune characteristics with IPAF, leading to suggestions that UIPAF could be reclassified, while highlighting that its management and prognosis align closely with