expansion of human disc chondrocytes from surgically removed disc tissue: Post-operative tissue stability.

Cell therapy using autologous, expanded chondrocytes from surgically removed disc tissues has emerged as a promising treatment option for patients with degenerated intervertebral discs. One critical aspect of this is the requirement to culture cells in a good manufacturing practice (GMP)-compliant tissue culture facility. Given the potential for delays during the transportation of disc tissue to a centralized cell culture facility, our study aimed to assess the stability of surgically removed disc tissues stored appropriately for varying durations.