Publications by authors named "Sarah Taieb"
Embryos derived from single pronucleus are suitable for preimplantation genetic testing.
Fertil Steril
October 2024
Objective: To study and compare the preimplantation genetic testing for monogenic disorders (PGT-M) results, and to evaluate the treatment cycle outcomes of embryos derived from a single pronucleus (1PN) vs. two pronuclei (2PN).
Design: A retrospective cohort study from January 2018 to December 2022 involving in vitro fertilization (IVF)-PGT-M treatment cycles.
Article Synopsis
- Monkeypox is a zoonotic disease originally from Africa that recently saw a global outbreak starting in April 2022, with limited understanding of its transmission.
- This observational study analyzed anal symptoms in 65 men diagnosed with monkeypox at a proctology unit in Paris during mid-2022, focusing on the association with sexually transmitted infections.
- Key findings revealed that a high percentage of cases involved sexual transmission, primarily among men who have sex with men, with common symptoms being painful anal and perianal ulcerations, and most patients experienced complete symptom resolution within 12 days.
Article Synopsis
- - The study aimed to evaluate how often severe bleeding occurs after proctological surgery and to identify risk factors, especially in the context of guidelines for anticoagulant treatment.
- - Out of 8,890 patients, only 0.7% required a hemostatic procedure, with a higher risk after hemorrhoidal surgeries, particularly the Milligan-Morgan procedure; blood transfusion was rare (0.1%).
- - Findings indicated that the use of anticoagulants and platelet inhibitors, when managed according to recommendations, did not increase bleeding risk; surprisingly, active smokers had a lower risk of severe bleeding compared to non-smokers.
Liver function test abnormalities are associated with a poorer prognosis in Covid-19 patients: Results of a French cohort.
Clin Res Hepatol Gastroenterol
September 2021
Aim: To assess the impact of liver function test (LFT) abnormalities on the prognosis of patients with coronavirus disease 2019 (COVID-19) in a French cohort of hospitalized patients.
Patients And Method: From March 13 to April 22, 2020, we collected on a computerized and anonymized database, medical records, laboratory data and clinical outcomes of patients hospitalized for confirmed cases of COVID-19 infection (RT-PCR and/or CT-scan). Patients were followed up until April 22, 2020 or until death or discharge.
Background: Regimens combining oxaliplatin with fluorouracil and folinic acid are standard therapeutic options for patients with metastatic colorectal carcinoma. Oxaliplatin has a good safety profile, although it is responsible for dose-limiting neurotoxicity typically consisting of two distinct clusters of symptoms. Cold-induced distal paresthesiae occur during or shortly after infusion in most patients and are usually transient and mild.
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