Infection of Bronchial Epithelial Cells by the Human Adenoviruses A12, B3, and C2 Differently Regulates the Innate Antiviral Effector APOBEC3B.

Human adenoviruses (HAdVs) are a large family of DNA viruses that include more than 100 genotypes divided into seven species (A to G) and induce respiratory tract infections, gastroenteritis, and conjunctivitis. Genetically modified adenoviruses are also used as vaccines, gene therapies, and anticancer treatments. The APOBEC3s are a family of cytidine deaminases that restrict viruses by introducing mutations in their genomes.

[Time in a rehabilitation unit].

In a rehabilitation unit, time is organised and activities punctuate the patient's and health professionals' day. This time is interspersed with the time of perception, time for thinking and anxiety, slow time, sequenced by the acceptance of the disability.

"What pressure ulcers mean to me?" Representations of pressure ulcer in persons with spinal cord injury: A qualitative study.

Objectives: Explore the perceptions and beliefs related to pressure ulcers (PU), their prevention and treatment strategies, in order to discuss potential learning objectives for PU-related therapeutic education in persons with spinal cord injury (SCI).

Design: Qualitative study, using grounded theory for the analysis of data collected via a questionnaire.

Setting: Nine SCI referral centers, inpatient care.

Transient improvement of poststroke apathy with zolpidem: a single-case, placebo-controlled double-blind study.

We report the case of a 44-year-old patient with severe and disabling apathy nearly 2 years after a right hemisphere haemorrhagic stroke. The effect of a single dose of zolpidem was tested over a 2-week period, in alternation with either no treatment or a placebo in a double-blind randomised trial. Zolpidem was associated with a dramatic improvement in apathy, as assessed with the Apathy Inventory and the Behavioral Dysexecutive Syndrome Inventory.