Publications by authors named "Sarah Demouche"
Background: Since the 2002 SCAR study, erythema multiforme (EM), a post-infectious disease, has been distinguished from Stevens-Johnson syndrome (SJS), drug-induced. Nevertheless, EM cases are still reported in the French pharmacovigilance database (FPDB).
Objectives: To describe EM reported in the FPDB and to compare the quality and the characteristics of the reports.
Article Synopsis
- * Research involving gene expression profiling of skin biopsies from DI-Pso patients revealed significant activation of the T helper 17/IL-23 pathways, alongside increased IL-36 expression, which is a marker of pustular psoriasis.
- * The findings indicate a shift in immune response from T helper 2 to T helper 17 in DI-Pso cases, coupled with notable skin barrier dysfunction compared to healthy individuals and those with other skin conditions.