Optimizing Tacrolimus Dosing During Hospitalization After Kidney Transplantation: A Comparative Model Analysis.

BACKGROUND The optimization of tacrolimus dosing during the early postoperative hospitalization period is essential to prevent rejection, minimize nephrotoxicity, and minimize the risk of opportunistic infections. Patient pharmacokinetic variability poses challenges in dose adjustment. This study aimed to evaluate tacrolimus dosing optimization using machine learning and statistical methods.

Efficacy of blood flow measurement using intraoperative color flow Doppler ultrasound as a predictor of autologous arteriovenous fistula maturation.

Introduction: Hemodialysis vascular access parameters of intraoperative Color flow Doppler ultrasound remain controversial. This study aimed to evaluate the optimal cut-off value and efficacy of intraoperative arteriovenous fistula parameters identified by Color flow Doppler ultrasound for arteriovenous fistula maturation success.

Methods: This retrospective study consisted of a review of the medical records of 137 consecutive patients who underwent their first autologous arteriovenous fistula formation under local anesthesia for end-stage renal disease from April 9, 2020 to March 19, 2021.

Efficacy of Lymphatic Sealing Using the LigaSure in Kidney Transplantation: A Pilot Study.

Background: Iliac vessel lymphatic ligation is critical in kidney transplantation, because it is associated with the occurrence of lymphocele. Lymphocele can also affect the renal graft. This study aimed to evaluate the efficacy of lymphatic sealing using LigaSure (an electrothermal bipolar sealing device) in kidney transplantation as compared with conventional silk-tie ligation.