Publications by authors named "Sami Simsek"

Coenurus cerebralis, the larval stage of Taenia multiceps, is a significant parasitic threat to small ruminants, yet its molecular diversity remains underexplored in many endemic regions. This study investigated the genetic variability of C. cerebralis from sheep in Elazig province, Türkiye, by analyzing mitochondrial CO1 (812 bp) and NADH1 (498 bp) gene regions.

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Cystic echinococcosis, caused by Echinococcus granulosus sensu stricto (G1/G3), is a major zoonosis with a complex transmission cycle. This study aimed to evaluate the mitochondrial genetic stability of E. granulosus s.

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Cystic echinococcosis (CE), caused by the larval stage of Echinococcus granulosus sensu lato, remains a major public health and veterinary concern. This study investigated the diagnostic potential of three parasite-derived microRNAs (miR-71, let-7-5p, and miR-2b-5p) in the serum of experimentally infected lambs. Protoscoleces isolated from sheep liver hydatid cysts were used to infect puppies, from which viable eggs were harvested and administered to newborn lambs (n = 11); uninfected lambs (n = 3) served as controls.

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Accurate species discrimination based on a robust nuclear protein-coding gene marker is essential for Fasciola spp. because of the presence of F. hepatica, F.

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Cystic Echinococcosis (CE) is one of the most common helminth infections in many parts of the world. Antigen B (AgB) is a key molecule secreted by both the germinal membrane and protoscoleces during the larval stages of Echinococcus granulosus. Characterizing polymorphisms in the genes encoding AgB can improve the interpretation of serological diagnostic tests.

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Echinococcus granulosus is a zoonotic helminth responsible for cystic echinococcosis, a significant public health concern. The diagnosis of E. granulosus infections in definitive hosts, such as dogs, is challenging due to the absence of clinical signs.

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Background: Red foxes (Vulpes vulpes) are hosts to a large number of endoparasites, some of which are zoonotic. This study was carried out to identify and molecularly characterise intestinal helminths in foxes in Bingol province, eastern Türkiye. For this purpose, carcasses of 15 red foxes that died as a result of traffic accidents in Bingol province were obtained.

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Cystic echinococcosis (CE), caused by Echinococcus granulosus sensu lato, is a significant zoonotic disease with profound public health and economic impacts. This study evaluated egg detection methods, molecular diagnostics, and post-treatment shedding dynamics in experimentally infected dogs. Three three-month-old male dogs were included in the study.

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Cystic echinococcosis is a severe zoonotic disease caused by different species and genotypes belonging to the Echinococcus granulosus sensu lato (s.l.) complex.

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Background: Echinococcus granulosus is a zoonotic disease that is widespread worldwide.

Objective: This study aimed to determine the genetic diversity of E. granulosus isolates in sheep.

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Cystic echinococcosis (CE) is one of the most significant zoonotic diseases globally, affecting both humans and livestocks. The aim of this study was to compare the efficacy of ultrasound (US) and serological methods as early diagnostic markers for both post-infection and post-treatment follow-up of CE in experimentally infected sheep. An hydatid cyst fluid was aspirated and 20,000 viable protoscoleces were administered orally to a dog.

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Taenia multiceps is found in canids and in its larval stage is known as Coenurus cerebralis causes coenurosis. The disease has a significant impact on the economic value of sheep and goats. The aim of the current study was to identify multiple cysts in the brain of a sheep displaying common symptoms of C.

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Varroa species, commonly known as the honey bee mites, poses a significant challenge to the worldwide beekeeping industry. The aim of this study was to investigate the effect of haplotype variation on morphology of Varroa destructor. Forty-one apiaries across Bingol province (Türkiye) and its districts were visited using random sampling to examine 2440 honey bee colonies.

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Article Synopsis
  • Fascioliasis, a disease caused by the parasite Fasciola hepatica, affects livestock, wildlife, and humans worldwide and can lead to significant health issues.* -
  • This study focused on identifying a Fasciola isolate from a brown bear by examining internal organs, where the parasite was found in the bile ducts and confirmed as F. hepatica through morphological analysis.* -
  • The research included DNA analysis, where a specific mitochondrial gene was amplified and sequenced, ultimately marking it as the first report of F. hepatica in brown bears and detailing its molecular characteristics.*
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  • - Macracanthorhynchus hirudinaceus is a zoonotic parasite found in the small intestines of wild boars, causing economic harm and posing public health risks.
  • - The study analyzed the damage to the small intestine of wild boar due to this parasite, identifying significant tissue damage characterized by crater-like ulcers and destruction of intestinal structures.
  • - Genetic analysis revealed that this parasite is endemic to Turkey, with the discovery of multiple haplotypes that could influence its epidemiology and pathology in the region.
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  • Wild boars can transmit zoonotic helminths to humans, and this study focused on identifying and characterizing these parasites found in wild boar carcasses from the 2023 hunting season.
  • The examination of 23 carcasses revealed the presence of Cysticercus tenuicollis and hydatid cysts, with molecular analysis identifying specific genotypes.
  • The results indicated that the G1 genotype of hydatid cysts was the most common among the studied wild boar population, along with the discovery of five new haplotypes, highlighting significant genetic diversity in these parasites.
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Article Synopsis
  • The study focused on the genetic variations and haplotypes of Cysticercus tenuicollis, a parasitic larval stage of the cestode Taenia hydatigena found in sheep and goats in Turkey.
  • Researchers collected samples from 44 sheep and 26 goats, isolating genomic DNA and analyzing the mitochondrial cytochrome oxidase 1 (CO1) gene to determine genetic diversity and relationships among the isolates.
  • Results showed 34 different haplotypes, high genetic diversity, and indications of population expansion, suggesting strong evolutionary dynamics within the C. tenuicollis populations.
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Cystic echinococcosis (CE) is a disease that can be transmitted from animals to humans, caused by the metacestode of Echinococcus granulosus. The disease has significant health and economic impacts worldwide, particularly in endemic areas. The study aimed to evaluate the prevalence of hydatid cysts in ruminants (cattle and sheep) (n = 2060) from the Setif Province of Algeria using microscopy.

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Cystic echinococcosis (CE) is a common zoonotic disease caused by the larval form of Echinococcus granulosus sensu lato. This study determined the genotype and haplotype differences using the NADH dehydrogenase subunit 5 gene in hydatid cyst samples. Human (n = 12), cattle (n = 28), and sheep (n = 31) hydatid cyst isolates were included.

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Purpose: Ligulosis caused by Ligula intestinalis adversely affects the fisheries carried out in the lakes and ponds, causing economic losses in the fish industry. In this study, it was aimed to reveal the molecular characterization of L. intestinalis isolates obtained from woodfish (Acanthobrama marmid) in Keban Dam Lake in Elazig province of Turkey by using mt-CO1 gene sequences and to determine the genetic differences and haplotypes between the isolates.

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Cystic echinococcosis, which is caused by the Echinococcus granulosus. Carnivores, as final hosts, contain adult tapeworms in the small intestine, and a variety of mammals, including humans, harbor the metacestod. This study was designed to investigate the miRNA-based biomarkers for early and accurate diagnosis of E.

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Article Synopsis
  • * The study collected 100 CE cyst samples from cattle and buffalo in Rawalpindi and Peshawar to determine the species and genetic diversity of E. granulosus in these animals.
  • * Results indicated that E. granulosus s.s. was the most common species found, with E. ortleppi identified for the first time in Pakistan, highlighting the need for further research to enhance control measures against CE.
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