Sarcoidosis presenting with massive splenomegaly: 2 cases without pulmonary involvement.

Sarcoidosis is a chronic systemic granulomatous disease presenting in the lungs and mediastinal lymph nodes. Extrapulmonary disease alone is rare and involvement of the spleen alone, in the absence of the lung, is even rarer. Splenomeglay is unusual as a first symptom and gives a diagnostic problem, especially in areas with high prevalence of infectious or haematologic diseases.

Skull bone lytic lesions: A rare form of multifocal skeletal tuberculosis.

Tuberculosis (TB) is a complex disease that can mimic numerous diseases involving different organ systems, making diagnosing TB challenging. Multifocal tubercular osteomyelitis is a rare form of skeletal TB that represents only a minority of all skeletal TB cases. Our patient, a 24-year-old immunocompetent male, complained of a low-grade fever that rises in the evening, scalp aches, right-sided chest pain, and non-inflammatory back pain with rest pain for six months.

Dengue Myocarditis: A Retrospective Study From 2019 to 2023 in a Tertiary Care Hospital in Bangladesh.

Background A major global health problem is dengue illness, which is rising in Bangladesh between 2019 and 2023. Dengue infections can present with a wide range of symptoms, from fever to severe organ involvement like myocarditis. In this retrospective analysis, risk factors, clinic-laboratory profile, and outcomes of dengue myocarditis in hospitalised patients were investigated.

Musculoskeletal Disorders in Elderly Patients With Diabetes Mellitus in a Rural Community of Bangladesh.

Background Among the elderly population of Bangladesh, diabetes mellitus (DM) is highly prevalent. DM has a strong relationship with musculoskeletal (MSK) disorders responsible for chronic pain, disability, and morbidity. Nevertheless, MSK disorder data of elderly diabetics are scarce in the literature, particularly in rural setups.

Dynamics of SARS-CoV-2 Immunoglobulin G Antibody Among Hospitalized Patients and Healthcare Workers During the Delta Wave in Bangladesh.

Background:  A reliable marker of COVID-19 past infection is the anti-spike IgG antibody (Ab) titer of the SARS-CoV-2 virus, which may be identified even one year from diagnosis. Serology can be effective in diagnosing asymptomatic infection and patients with negative reverse transcription polymerase chain reaction. Exploring these dynamics and the persistence of antibodies is vital to understanding the disease process.

Glycemic Control Status After Six Months in Post-COVID-19 Patients.

Background Despite being typically a viral respiratory disease, COVID-19 has harmful effects that go beyond the respiratory system. The endocrine system is particularly susceptible to damage due to the high expression of angiotensin-converting enzyme-2 receptors. This study evaluates glycemic status in survivors of COVID-19.

A case of typhoid fever with neurological presentation.

Introduction: Typhoid fever, leading to systemic disease due to Salmonella enterica serotype Typhi, typically has gastrointestinal manifestation, however, neurologic complications-although uncommon, can arise. Aseptic meningitis and optic neuritis are rare manifestations that can be challenging to diagnose.

Case Summary: Our patient a 31-year male presented with fever for 18 days associated with headache, rash, vomiting, diarrhea and progressive neurological symptoms in form of disorientation and blurred vision.

Role of Carcinoembryonic Antigen in Severity Assessment and Mortality Prediction in COVID-19 Patients.

Background Early risk stratification of COVID-19 may yield a better prognosis by tailoring effective treatment strategies. Recent studies have identified that elevated carcinoembryonic antigen (CEA) has prognostic value in terms of disease severity and mortality in patients with pneumonia. This study aims to explore the potential of CEA as a marker for both severity assessment and mortality prediction in COVID-19 patients.

Disseminated histoplasmosis: Long journey of a febrile young man.

A 19-year-old non-diabetic, non-HIV male presented with eighteen months of fever, weight loss, skin rash and lymphadenopathy. He was treated with anti-tubercular medication for more than twelve months in multiple institutions based on repeated biopsy reports of lymph nodes showing granuloma suggestive of tuberculosis. Before he was diagnosed at Bangabandhu Sheikh Mujib Medical University (BSMMU) with disseminated histoplasmosis at eighteen months of his disease, he already lost twenty kg weight, developed multiple small joint pain, back pain, and cough along with previously mentioned symptoms.

Clinical profile and early severity predictors of dengue fever: Current trends for the deadliest dengue infection in Bangladesh in 2022.

Objectives: In 2022, Bangladesh had the highest dengue-related fatality (281). This study evaluated clinical profiles to detect early changes to predict dengue fever severity.

Methods: This prospective observational study was performed in four government hospitals from June to November 2022 in Dhaka.

Multicentric Castleman Disease: The Hyaline Vascular Type Without HIV Association in a Young Male With Cutaneous Manifestation and Renal Impairment.

Castleman disease (CD), a heterogenous lymphoproliferative disorder resulting from immune dysregulation, is a very rare disease in clinical practice. The clinical spectrum of Castleman disease is wide and its treatment options are mostly based on case reports and case series. To date, two clinical and four histological types have been described.

Clinical Profile, Severity Spectrum, and Hospital Outcome of Dengue Patients in a Tertiary Care Hospital in Dhaka City.

Background Bangladesh saw its most severe dengue outbreak in 2019, with the highest number of deaths reported. This study investigated the clinical characteristics, severity spectrum, and potential outcomes of dengue in patients admitted to a tertiary care institution in Dhaka. Methods This prospective observational study was done between May 2019 to April 2020.

A Young Lady With Myopericarditis: An Unusual Presentation of COVID-19 Infection.

Fever, sore throat, cough, and shortness of breath are the characteristic clinical manifestations of coronavirus disease 2019 (COVID-19). As the epidemic spreads, it is evident that the infection can affect not only the lungs but also other organs. By attaching to the angiotensin-converting enzyme-2 receptor (ACE-2), the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces lung injury.

Disseminated mucormycosis: An unusual case of ascites with bone marrow invasion.

Mucormycosis is a fatal invasive illness most frequently seen in immunocompromised hosts with uncontrolled diabetes, hematological malignancies, organ transplantation, or long-term steroid treatment. It has a poorer outcome than other fungal diseases due to its rapid spread and resistance to antifungal agents. We report a rare case of disseminated mucormycosis including the bone marrow, peritoneum, lung, and lymph nodes in an apparently immunocompetent 58-year-old gentleman who presented with two months of ascites and weight loss.

A Young Female With Borderline Lepromatous Leprosy and Tuberculous Lymphadenitis: A Rare Coinfection.

In Bangladesh, tuberculosis and leprosy are endemic mycobacterial diseases; however, co-infection is rarely seen. Our patient had a high-grade fever, symmetrical polyarthritis, polymorphous erythematous lesions, widespread lymphadenopathy, peripheral neuropathy, bilaterally thickened ulnar nerves, and claw hands. A lymph node biopsy revealed tuberculosis having acid-fast bacilli with caseating epithelioid histiocytic granuloma.

Survey and analysis of consumers' behaviour for electronic waste management in Bangladesh.

This paper aims to establish consumer's perception of electric waste recycling and management on a national scale in Bangladesh. The attitude, willingness to pay (WTP) and consumers' behaviour were explored by conducting a questionnaire-based survey. The conclusions are based on 915 valid responses out of 2000 online survey invitations.

In vitro degradation and cell attachment studies of a new electrospun polymeric tubular graft.

Electrospinning technique was utilized to engineer a small-diameter (id = 4 mm) tubular graft. The tubular graft was made from biocompatible and biodegradable polymers polycaprolactone (PCL) and poliglecaprone with 3:1 (PCL:PGC) ratio. Enzymatic degradation effect on the mechanical properties and fiber morphology in the presence of lipase enzyme were observed.