Publications by authors named "Samed Simsek"
The essential oils of aerial parts of Hesperis isatidea were analyzed using gas chromatography-mass spectrometry for the first time in the present study. The major components were determined as benzyl salicylate (13.40%), phytol (9.
View Article and Find Full Text PDFThe aim of this study was to determine the secondary metabolites of the n-hexane, ethyl acetate, methanol, and water extracts of Achillea sintenisii Hub. Mor. and to ascertain their divergent biological properties.
View Article and Find Full Text PDFComprehensive phenolic profiling and biological evaluation of L. (Asteraceae).
Nat Prod Res
February 2025
The present investigation focused on the comprehensive analysis of the phenolic profile of L. (Asteraceae) and the assessment of its diverse biological activities. Utilising LC-MS/MS, the phytochemical composition of the 70% methanol extract of (CG-ME) was thoroughly elucidated, revealing the presence of 30 distinct phytochemical compounds.
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- This study explores the health benefits of Thymus pectinatus (TP) and Thymus convolutus (TC), focusing on their ability to fight cancer, provide antioxidants, and exhibit antimicrobial properties.
- Both plant extracts demonstrated high levels of phenolic and flavonoid compounds, with TP showing more flavonoids than TC.
- The extracts were effective against various cancer cell lines with minimal harm to normal cells, very potent at inhibiting an enzyme involved in oxidative stress, and showed noteworthy antimicrobial effects, particularly TP against certain bacteria.
Article Synopsis
- A new phenylethanoid compound called ferruginoside D was discovered alongside 14 known compounds from Verbascum leiocarpum, using advanced spectroscopic techniques to determine their structures.
- The isolated compounds were tested for their antioxidant effects, ability to inhibit α-glucosidase, and anti-cancer properties across various cell lines, showing promising results especially for iridoids and flavonoids like luteolin and apigenin.
- Specifically, ferruginoside D demonstrated moderate activity against cancer cells while exhibiting strong α-glucosidase inhibitory effects and moderate antioxidant capabilities.
Phytochemical analysis and biological evaluation of Ferulago setifolia K. Koch.
J Sci Food Agric
February 2024
Article Synopsis
- Researchers studied Ferulago setifolia (FS) to analyze its phenolic compounds and biological activities, identifying 23 phytochemicals, including key ones like chlorogenic acid and quercetin.
- The FS extract showed moderate antioxidant properties and strong antiproliferative effects on cancer cells with minimal harm to normal cells, as well as effective antibacterial activity against several harmful bacteria.
- Findings suggest FS could be beneficial for developing pharmaceuticals and industrial products due to its active compounds and health benefits.
Geographic conditions (altitude, climate, and local flora) lead to significant differences in the chemical composition of propolis. Therefore, more research is needed for propolis in different geographical regions. So, the aim of this study was to evaluate the phenolic profile, total phenolic content, antioxidant, and antidiabetic properties of Pülümür propolis from Turkey.
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