Fourier transform infrared spectroscopy as a new tool to investigate Clostridioides difficile outbreaks: A proof-of-concept study.

Whole genome sequencing (WGS), used as the main method for outbreak investigations, requires substantial technical expertise and is routinely done by reference laboratories. Therefore, the actionable information is often delayed. This study is the first to assess Fourier Transform Infrared (FTIR) spectroscopy as an alternative tool to investigate nosocomial Clostridioides difficile transmission.

Toxoplasma gondii and schizophrenia: a review of published RCTs.

Over the last 60 years, accumulating evidence has suggested that acute, chronic, and maternal Toxoplasma gondii infections predispose to schizophrenia. More recent evidence suggests that chronically infected patients with schizophrenia present with more severe disease. After acute infection, parasites form walled cysts in the brain, leading to lifelong chronic infection and drug resistance to commonly used antiparasitics.

A program to identify prognostic and predictive gene signatures.

Background: The advent of high-throughput technologies to profile human tumors has generated unprecedented insight into our molecular understanding of cancer. However, analysis of such high dimensional data is challenging and requires significant expertise which is not routinely available to many cancer researchers.

Results: To overcome this limitation, we developed a freely accessible and user friendly Program to Identify Molecular Signatures (PIMS).