Publications by authors named "Saleem M Halablab"

Out-of-hospital cardiac arrest (OHCA) represents a significant global public health burden, characterized by low survival and few established diagnostic tools to guide intervention. OHCA presents with a wide variety of etiologies in a heterogeneous population, posing a clinical challenge to care teams. In this review, we describe evolving research focused on diagnostic approaches to OHCA following resuscitation, including electrocardiography, coronary angiography, computed tomography, ultrasonography, and serologic biomarker assessment.

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Patients with atrial fibrillation (AF) taking antithrombotic (AT) therapy are at an increased risk of gastrointestinal bleeding (GIB). The comparative effect of a combination of anticoagulant (AC) and antiplatelet (AP) versus AC monotherapy on clinical outcomes in patients with AF presenting with GIB is not well characterized. This study compares outcomes in AF patients with GIB on AC alone with those on combination AP and AC therapy, as part of a larger prospective study from 2013 to 2023.

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Importance: In-hospital cardiac arrest (IHCA) is a significant public health burden. Rates of return of spontaneous circulation (ROSC) have been improving, but the best way to care for patients after the initial resuscitation remains poorly understood, and improvements in survival to discharge are stagnant. Existing North American cardiac arrest databases lack comprehensive data on the post-resuscitation period, and we do not know current post-IHCA practice patterns.

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Article Synopsis
  • The study explores how smoking affects the need for surgery in patients with moderate to severe Crohn's disease (CD) undergoing biologic therapy, noting its harmful effects on CD and protective effects on ulcerative colitis.
  • The retrospective analysis included 251 adults with CD over 20 years, revealing that smoking status did not significantly impact surgery rates overall, but smokers were more likely to require perianal surgery before starting biologics.
  • The findings suggest that while smoking is linked to increased perianal surgical needs in biologic-naive patients, other factors like disease duration and the number of biologics used are more critical in predicting surgery after treatment initiation.
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