Publications by authors named "Sajjad Ataei-Azimi"
Factor XIII (FXIII) deficiency is a rare coagulopathy with an estimated prevalence of approximately 1 in 1 to 2 million, affecting males and females with equal frequency. FXIII plays a critical role in hemostasis by stabilizing fibrin clots through covalent cross-linking of fibrin monomers, thereby conferring mechanical resistance and durability to the clot structure. Clinically, FXIII deficiency presents with a spectrum of hemorrhagic manifestations including bleeding from the umbilical cord, intracranial hemorrhage, recurrent miscarriages, menorrhagia, epistaxis, gingival bleeding, and poor wound healing.
View Article and Find Full Text PDFBackground: Anthracycline drugs play a fundamental role in breast cancer treatment; however, the cardiotoxicity side effects obscure the advantages of treatment. Curcumin has antioxidant and anti-inflammatory effects.
Materials And Methods: In this study, we investigated the effect of nanocurcumin supplementation on Doxorubicin induced Cardiotoxicity.
The evaluation of atorvastatin as an adjunct to fluconazole for the anti-fungal prophylaxis in acute myeloid leukemia: a multicenter, triple-blinded, randomized clinical trial.
Naunyn Schmiedebergs Arch Pharmacol
June 2024
Article Synopsis
- * Conducted among 76 AML patients in a multicenter, triple-blind setup, the research found that atorvastatin significantly reduced the incidence of IFIs compared to a placebo, leading to better IFI-free survival rates.
- * No severe side effects from atorvastatin were reported, supporting previous findings about the antifungal properties of statins and highlighting the need for further research with larger groups and longer follow-ups.
Background And Aims: The effect of stopping or reducing the dose of vincristine in diffuse large B-cell lymphoma (DLBCL) on the outcome and prognosis of the disease is still in doubt. The present study aimed to investigate and compare the prognosis and complete remission of two R-CHOP treatment regimens with and without vincristine reduction in DLBCL patients.
Methods: This retrospective study was conducted on newly diagnosed DLBCL patients during 2018-2021.
Acute macular neuroretinopathy in a patient with acute myeloid leukemia and deceased by COVID-19: a case report.
J Ophthalmic Inflamm Infect
January 2021
Purpose: Acute macular neuroretinopathy (AMN) is a visual-deteriorating rare clinical entity with an uncertain etiology. We aimed to report a case of AMN and underlying disease of acute myeloid leukemia (AML).
Case Presentation: A thirty-five-year-old female patient with bone marrow biopsy confirmed AML, and bicytopenia, under chemotherapy, complained of sudden paracentral visual field defect in her right eye was referred.