Associations of elevated pro-inflammatory cytokines Interleukin-6, C-reactive protein and tumor necrosis factor alpha with neuropsychiatric symptoms of post-acute sequelae of COVID-19 (PASC).

Background: This cross-sectional study investigated the prevalence of clinically elevated interleukin 6 (IL-6), C-reactive protein (CRP) and tumor necrosis factor-alpha (TNF-α), and explored their associations with sociodemographic, medical, and neuropsychiatric symptoms of Post-acute Sequelae of COVID-19 (PASC).

Method: Participants were assessed for acute and current COVID-19 symptomatology, measures of distress and neuropsychological testing approximately 6 months (mean 183 days, SD 137 days, range 30-598 days) after acute infection. Serum IL-6, CRP and TNF-α levels were drawn from 80 participants concurrently.

Characteristics of Calls to a COVID-19 Mental Health Hotline in the First Wave of the Pandemic in New York.

This report describes the development, implementation and outcomes of a "COVID-19 Anxiety Hotline," designed to address the community's mental health crisis provoked by the coronavirus pandemic. The service was specifically designed using survey data regarding the effects of the COVID-19 pandemic on its staff and community members. Callers had around-the-clock direct access to mental healthcare providers at no cost.