Photocatalytic oxidative hydroacylation with alcohols.

Herein, we report a photocatalytic method for oxidative hydroacylation with alcohols. Under photoirradiation and a catalytic amount of TBADT, different electrophiles (azodicarboxylates, -phenylmaleimide, benzylidenemalononitrile and phenyl vinyl sulfone) underwent hydroacylation with alcohols in good yields. The method was also applied to achieve a convenient synthesis of the anti-depressant drug moclobemide.

Organocatalytic photoinduced carboamination of dienes.

An organocatalytic photoinduced 1,2-carbofunctionalization strategy for conjugated dienes has been developed. No exogenous photocatalyst or additives are required in this mild protocol and it allows for highly regioselective and efficient 1,2-carboisothiocyanation through the coupling of a diene, an alkyl radical and TMSNCS. The reaction is proposed to proceed through EDA complexation between the diene and TMSNCS.