Adapting gas fermenting bacteria for light-driven domino valorization of CO.

The solar-driven valorization of CO to fuels and chemicals provides an exciting opportunity to develop a circular chemical industry, but the controlled production of multicarbon organics remains a major challenge. Here, we present an abiotic-biotic domino strategy that integrates a photocatalytic CO-to-syngas conversion system with evolved syngas-fermenting bacteria to enable the upcycling of CO into valuable C products, including acetate and ethanol. To optimize microbial syngas fermentation through an accessible and chemist-friendly platform, we employ adaptive laboratory evolution (ALE) of ().

Evaluating the effects of zinc hydroxychloride on intestinal barrier permeability and biomarkers of inflammation and metabolism during and following heat stress.

Heat stress (HS) jeopardizes dairy cow productivity and health. Gastrointestinal tract (GIT) barrier dysfunction appears to be the etiological epicenter of HS-induced pathology. However, the physiology of recovery from HS has scarcely been studied in dairy cows.

Bio-Inspired Self-Assembly of Enzyme-Micelle Systems for Semi-Artificial Photosynthesis.

Supramolecular surfactants provide a versatile platform to construct systems for solar fuel synthesis, for example via the self-assembly of amphiphilic photosensitizers and catalysts into diverse supramolecular structures. However, the utilization of amphiphilic photosensitizers in solar fuel production has predominantly focused on yielding gaseous products, such as molecular hydrogen (H), carbon monoxide (CO), and methane (CH) with turnover numbers (TONs) of synthetic catalysts typically in the range of hundreds to thousands. Inspired by biological lipid-protein interactions, we present herein a bio-hybrid assembly strategy that utilizes photosensitizers as surfactants to form micellar scaffolds that interface with enzymes, namely hydrogenases and formate dehydrogenases, for semi-artificial photosynthesis.

Intermittent and increasing intravenous lipopolysaccharide effect on metabolism, inflammation, and production in lactating dairy cows.

Experimental objectives were to create a chronic inflammatory model to evaluate the effects of persistent immune activation on metabolism, inflammation, and productivity in lactating dairy cows. Twelve lactating Holstein cows (631 ± 16 kg BW; 124 ± 15 DIM) were enrolled in a study with 2 experimental periods; during period 1 (P1; 5 d), cows were fed ad libitum and baseline data were obtained. At the initiation of period 2 (P2; 7 d), cows were assigned to 1 of 2 treatments: (1) saline infused and pair-fed (PF; 5 mL i.

Comparing oral versus intravenous calcium administration on alleviating markers of production, metabolism, and inflammation during an intravenous lipopolysaccharide challenge in mid-lactation dairy cows.

Animals, including dairy cows, develop hypocalcemia during infection. Prior independent research suggests supplementing oral Ca, but not i.v.