In this study, we report the improved photocatalytic performance of Hydroxyapatite-incorporated Zinc Oxide Nanocomposite (ZnO@HAp), synthesized using a simple precipitation method. The catalyst was characterized using powder X-ray diffraction (XRD), Fourier transform infrared spectroscopic analysis (FT-IR), Ultraviolet-Visible Diffuse Reflectance Spectroscopy (UV-DRS), Scanning Electron Microscopy (SEM) with energy-dispersive X-ray spectroscopy (EDX), and X-ray photoelectron spectroscopy (XPS). The formation of ZnO@HAp was confirmed by XRD, FT-IR, EDAX, and XPS.
View Article and Find Full Text PDFJ Immunother Cancer
August 2025
BackgroundMicrobiome manipulation research is focused on developing techniques to modify the gut microbiome and augment responses to immune checkpoint inhibitors (ICI). Fecal microbiota transplantation (FMT) represents a potential strategy to overcome primary or acquired resistance to ICI. 20 patients with advanced melanoma were enrolled in a phase I multicenter trial to evaluate the safety and response to anti-PD1 combined with FMT using healthy donor stool as first-line treatment (MIMic, NCT03772899).
View Article and Find Full Text PDFThe global food system's unsustainable practices present considerable environmental risks while fulfilling essential nutritional needs. This study presents a comprehensive evaluation of the environmental impacts associated with commonly consumed food items in India. It focuses on eighteen representative products, grouped into five major food categories, and uses a production-focused Life Cycle Assessment (LCA) approach to analyze their environmental performance.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
June 2025
Aim: To evaluate the antimicrobial efficacy of different irrigants combined with silver nanoparticles.
Materials And Methods: Thirty-five patients were divided into seven groups (two control and five experimental), including Group 1: negative control (normal saline), Group 2: positive control (sodium hypochlorite), and Group 3 (sodium hypochlorite + AgNP), Group 4 (Twin Kleen), Group 5 (Twin Kleen + AgNP), Group 6 (Q Mix), and Group 7 (Q Mix + AgNP). Pre- and post-treatment bacterial samples were collected for analysis.
BackgroundPulpotomy is widely used in primary and immature permanent teeth, but its effectiveness in mature permanent teeth with irreversible pulpitis remains controversial.ObjectiveTo identify and evaluate the existing systematic reviews of randomized controlled trials (RCTs) assessing pulpotomy as a treatment for irreversible pulpitis in mature permanent teeth.MethodsA protocol-guided search was conducted across PubMed, ProQuest, EMBASE, and Cochrane up to March 2024, targeting systematic reviews based on RCTs.
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