Dosimetric accuracy of low dose rate volumetric modulated arc therapy delivery in an Elekta Versa HD linear accelerator for pulsed low dose rate treatment of recurrent high-grade glioma using Monaco planning system: Low dose rate VMAT-based PLDR in Elekta Linac.

Background And Purpose: Reducing the dose rate enhances efficacy in radiation therapy by allowing increased repair of sub-lethal damage. Pulsed low-dose radiation therapy (PLDR) is an innovative approach that is safe and effective for the reirradiation of recurrent gliomas and radioresistant tumors. In this study, the accuracy of the low dose rate volumetric modulated arc therapy (VMAT) delivery is tested in an Elekta Versa HD linear accelerator (linac) for delivering PLDR.

Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 13C, 1H and UV) investigations of antiepileptic drug Ethosuximide.

The Fourier Transform Infrared (FT-IR) and Fourier Transform Raman (FT-Raman) spectra of antiepileptic drug Ethosuximide (ETX) have been recorded and analyzed. In addition, the IR spectra in CCl(4) at various concentrations of ETX are also recorded. The equilibrium geometry, bonding features and harmonic vibrational frequencies have been investigated with the help of Density Functional Theory (DFT) method.