Publications by authors named "S M Al-Rawashdeh"

Objective: Studies have reported a lower incidence of postpartum depression, anxiety, and perceived stress among exclusive breastfeeding mothers compared to non-exclusive and formula-feeding mothers. However, the molecular mechanisms underlying the protective action of exclusive breastfeeding against these mental disorders remain unclear. This study examined the differences between exclusive and non-exclusive breastfeeding mothers in terms of postpartum depression, anxiety, and perceived stress, measured subjectively and objectively (based on cortisol, immunoglobulin A, and ghrelin saliva levels).

View Article and Find Full Text PDF

Background: Alcohol use continues to be a global public health concern that significantly contributes to economic burden and increased morbidity and mortality rates. Healthcare professionals, including nurses and behavioral health professionals, play a vital role in alcohol use prevention, screening, and management. The purpose of this study is to identify nurses' and behavioral health professionals' demographic and clinical characteristics and professional attitudes as predictors of their motivation toward providing care related to alcohol use.

View Article and Find Full Text PDF

Autoimmune diseases (ADs) impact approximately 3% of the global population. It encompasses more than 80 chronic, often debilitating conditions resulting from immune system defects that lead the body to attack its tissues. Although many ADs are rare, their prevalence is rising.

View Article and Find Full Text PDF
Article Synopsis
  • Cardiovascular diseases, particularly hereditary Long QT Syndrome (LQTS), are linked to ion channel dysfunctions, leading to a higher risk of sudden cardiac death, especially with the LQT2 type caused by mutations in the hERG gene.
  • Specific high-affinity hERG blockers like E-4031 could potentially rescue these dysfunctional channels, but the mechanisms behind their effectiveness are unclear.
  • The study employs accelerated molecular dynamics simulations to show how mutations in the hERG channel alter its structure and trafficking, and suggests that E-4031 may inhibit these detrimental changes, paving the way for new treatments targeting the underlying cellular issues.
View Article and Find Full Text PDF

Background: The World Health Organization recommended the use of chemical-based disinfectants as an effective prevention of the COVID-19 pandemic. However, calls for poisoning were reported in several medical centers. The widespread use of chemical-based disinfectants as a preventive measure during the COVID-19 pandemic has underscored potential gaps in community awareness and performance, posing health risks.

View Article and Find Full Text PDF