Number, depth, and location of inadvertent pancreatic guidewire cannulations and post-ERCP pancreatitis from multicenter real-time intra-procedural data.

Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is common. Although multiple pancreatic duct (PD) cannulations are a known risk factor for PEP, the impact of single cannulations remains controversial. We aimed to identify whether single PD cannulation is associated with PEP.

Self-Injection Satisfaction and Safety of CT-P17 (Yuflyma), a High-Concentration Adalimumab Biosimilar, in Patients With Crohn's Disease: A Cross-Sectional Study.

Background: CT-P17 (Yuflyma), a biosimilar to adalimumab (Humira), offers a cost-effective alternative with improved access for individuals with immune-mediated inflammatory diseases (IMIDs). Assessing patient experience with autoinjector usability and comfort is crucial for ensuring adherence and satisfaction. This study is the first to evaluate patient-reported satisfaction and safety of CT-P17 specifically in people with Crohn's disease (CD).

Exploring the ecological feasibility of restoring Eurasian lynx to Great Britain using spatially explicit individual-based modelling.

Ecological restoration offers a multitude of benefits for the human-nature system, which has put it at the forefront of international initiatives opposing environmental degradation. In Great Britain, the reintroduction of Eurasian lynx has been proposed to help improve ecosystem health, raising the question; what is the ecological feasibility of lynx reintroduction in Great Britain? Combining a lynx-specific spatially explicit individual-based model and contemporary habitat suitability mapping would shed new light on this question. We hypothesised potential drivers of reintroduction success, including demographic parameters, behavioural responses in habitat selection, and management strategies.

Adverse events, success, and tolerability of biliary endoscopic retrograde cholangiopancreatography with conscious sedation vs anaesthesia: a multi-centre prospective study.

Background And Aims: Endoscopic retrograde cholangiopancreatography (ERCP) is performed using anaesthesia or conscious sedation, though the effectiveness, adverse events (AEs), and tolerability of each approach remain unclear. Thus, we compared these approaches prospectively.

Methods: We performed a multi-centre prospective cohort study including patients with native papillae undergoing ERCP for biliary indications between 2018 and 2023.