Advancements in cyberthreat intelligence through resource exhaustion attack detection using hybrid deep learning with heuristic search algorithms.

The Distributed Denial of Service (DDoS) attack is uncontrollable and appears in different patterns and shapes; accordingly, it is not easily detected and solved with preceding solutions. A DDoS attack is the most serious threat on the Internet. These attacks became a preferred weapon for cyber extortionists, terrorists, and hackers.

A deep dive into artificial intelligence with enhanced optimization-based security breach detection in internet of health things enabled smart city environment.

Internet of Health Things (IoHT) plays a vital role in everyday routine by giving electronic healthcare services and the ability to improve patient care quality. IoHT applications and devices become widely susceptible to cyber-attacks as the tools are smaller and varied. Additionally, it is of dual significance once IoHT contains tools applied in the healthcare field.

Punishment-Induced Suppression of Methamphetamine Self-Administration Is Accompanied by the Activation of the CPEB4/GLD2 Polyadenylation Complex of the Translational Machinery.

Methamphetamine (METH) use disorder (MUD) is a public health catastrophe. Herein, we used a METH self-administration model to assess behavioral responses to the dopamine receptor D1 (DRD1) antagonist, SCH23390. Differential gene expression was measured in the dorsal striatum after a 30-day withdrawal from METH.

Insights into the interaction mechanism of first-generation HIV-1 protease inhibitors with wild-type and mutant (D30N and L76V) enzymes through based approach.

The combined effort of medical, scientific and pharmaceutical research has transformed the HIV infection from an inevitably fatal disease into a manageable chronic ailment. Especially after the introduction of protease (PR) inhibitors the efficacy of the treatment regimen has been increased. However, the development of mutant PR enzymes is a major concern.

Menopause mysteries: the exosome-inflammation connection.

Extracellular vesicles, or exosomes, are produced by every type of cell and contain metabolites, proteins, lipids, and nucleic acids. Their role in health and disease is to influence different aspects of cell biology and to act as intermediaries between cells. Follicular fluid exosomes or extracellular vesicles (FF-EVs) secreted by ovarian granulosa cells are critical mediators of ovary growth and maturation.