Biotransformation of Deoxynivalenol to the Novel Metabolite Deoxynivalenol-8,15-hemiketal-7-glucoside by the Glycosyltransferase YjiC.

The mycotoxin deoxynivalenol (DON) is a chronic problem in cereals in temperate areas worldwide. Above regulatory levels, DON contamination can result in significant economic loss both to the primary producer and the feed industry in terms of increased costs. Here we report the enzymatic biotransformation of DON to a novel stable metabolite by a soil-borne strain of .

International interlaboratory study to normalize liquid chromatography-based mycotoxin retention times through implementation of a retention index system.

Monitoring for mycotoxins in food or feed matrices is necessary to ensure the safety and security of global food systems. Due to a lack of standardized methods and individual laboratory priorities, most institutions have developed their own methods for mycotoxin determinations. Given the diversity of mycotoxin chemical structures and physicochemical properties, searching databases, and comparing data between institutions is complicated.

Genomic characterization of pathotype diversity and drug resistance among generic isolated from broiler chickens in Canada.

is a Gram-negative bacterium that is ubiquitous in animals and humans, with some strains capable of causing disease. The aim of this study was to perform a comparative genomic analysis of 2732 generic isolates that were recovered from poultry samples collected from six regions in Canada as part of the National Microbiological Baseline study in Broiler Chicken. Isolates were subjected to whole genome sequencing and a subset (1122/2732) were tested for phenotypic resistance to 15 antimicrobials.

Enzymatic Hydrolysis of Resorcylic Acid Lactones by an sp.

Zearalenone and radicicol are resorcylic acid lactones produced by numerous plant pathogenic fungi. Zearalenone is a non-steroidal estrogen mimic that can cause serious reproductive issues in livestock that consume contaminated feed. Radicicol is a potent inhibitor of the molecular chaperone Hsp90, which, in plants, has an important role in coordinating the host's immune response during infection.