A case report on the long-term use of teduglutide in a pediatric patient with short bowel syndrome.

Short bowel syndrome (SBS) is the leading cause of intestinal failure, frequently necessitating long-term parenteral nutrition (PN). Teduglutide (TED), a glucagon-like peptide-2 analog, has demonstrated efficacy in reducing PN dependence in both adults and children. However, long-term data in pediatric populations remain limited.

Sudden death in a Thoroughbred stallion: cardiac tamponade due to transverse aortic rupture with bone metaplasia and calcification.

A 17-year-old Thoroughbred stallion died suddenly after grazing. Necropsy revealed massive hemorrhage in the pericardial sac, suggesting cardiac tamponade. Aortic perforation was observed at the aortic origin, and hemorrhage was observed in and around the epicardium.

Clinical characteristics of multiple evanescent white dot syndrome with poor visual prognosis in Japanese patients.

Purpose: Multiple evanescent white dot syndrome (MEWDS) typically resolves spontaneously and is expected to have a favorable visual prognosis. Therefore, the initial manifestations of MEWDS have yet to be well studied. This study aimed to investigate the clinical characteristics of primary and secondary MEWDS patients and evaluate factors responsible for poor visual prognosis.

AI-based analysis of surgical outcomes in vitrectomy with and without cystotomy for refractory cystoid diabetic macular edema.

The aim of this study was to compare surgical outcomes in vitrectomy with and without cystotomy for refractory cystoid diabetic macular edema (DME). This study enrolled 35 eyes of 29 patients who underwent vitrectomy for refractory DME. The eyes were divided into 2 groups, those undergoing vitrectomy with cystotomy (cystotomy group) (n = 8) and vitrectomy with internal limiting membrane (ILM) peeling only (ILM peeling group) (n = 27).

Choroidal blood flow velocity and resistance in inferior posterior staphyloma using a novel superpixel technique in laser speckle flowgraphy.

This study examined choroidal circulation in inferior posterior staphyloma (IPS) eyes using mean blur rate (MBR) and beat strength over MBR (BOM) from laser speckle flowgraphy. Eighteen eyes from 12 patients with treatment-naïve IPS were studied, including 9 eyes with subretinal fluid (SRF). The thinnest part of the choroid was identified via optical coherence tomography, and rubber bands were placed at bordering across the superior and inferior regions.

Retinal Arteriovenous Information Improves the Prediction Accuracy of Deep Learning-Based baPWV Index From Color Fundus Photographs.

Purpose: To compare the prediction accuracy of brachial-ankle pulse wave velocity (baPWV) from color fundus photographs (CFPs) using different deep learning models.

Methods: This retrospective study analyzed the data of 696 participants whose baPWVs and CFPs were obtained during medical checkups. Arteriolar and venular probability maps, which were automatically calculated from the CFPs based on our modified deep U-net, Hokkaido University retinal vessel segmentation (HURVS) model, were applied as channel attention to retinal vessel location information to predict baPWV.

Differences in Artificial Intelligence-Based Macular Fluid Parameters Between Clinical Stages of Diabetic Macular Edema and Their Relationship with Visual Acuity.

: The aim of this study was to determine artificial intelligence-based macular fluid (MF) parameters in diabetic macular edema (DME) with optical coherence tomography (OCT) and examine stage-by-stage differences in MF parameters and their relationship with best-corrected visual acuity (BCVA). : This study enrolled 104 eyes with treatment-naïve DME. Intraretinal fluid (IRF) and subretinal fluid (SRF) were detected in horizontal OCT images based on the "Hokkaido University MF segmentation model" when DME was first observed together with BCVA testing.

An adult myogenic cell line of the Japanese fire-bellied newt Cynops pyrrhogaster.

Adult myogenic cell lines are useful to study muscle development, repair and regeneration. In newts, which are known for their high regenerative capacity, myogenic cell lines have not been established in species other than the Eastern newt Notophthalmus viridescens. In this study, we established another myogenic cell line, named CpM01, from the skeletal muscle of the forearm of the adult Japanese fire-bellied newt Cynops pyrrhogaster.

Ruminant stimulating device-associated esophageal obstruction in a Japanese black heifer with acquired esophageal diverticulum.

Esophageal diseases include esophageal obstruction, esophagitis, esophageal stricture, and esophageal diverticulum. Imaging can facilitate the selection of appropriate treatment options and assist in differential diagnosis. Esophageal obstruction in cattle is generally caused by greedy nature of chewing and swallowing of food and foreign structures, including stones, potatoes, trichobezoar, carrots, foodstuffs (i.

Malnutrition defined by global leadership initiative on malnutrition criteria impedes home discharge in acute care hospital admissions.

Background & Aims: Limited evidence exists on the association between malnutrition diagnosis using the Global Leadership Initiative on Malnutrition (GLIM) criteria in hospitalized acute care patients and their outcomes; several aspects still require clarification. This study aimed to evaluate the relationship between malnutrition, as defined by the GLIM criteria, at the time of acute hospital admission and discharge to home.

Methods: This retrospective observational study was conducted at a hospital that provides acute care in Japan.

Usefulness of central venous catheter replacement with a guidewire in patients with intestinal failure: a single-center study.

Purpose: Patients with intestinal failure (IF) require long-term parenteral nutrition using central venous catheters (CVCs), which often require replacement. We adopted a less fallible guidewire replacement (GWR) method and verified its effectiveness and validity.

Methods: We enrolled 108 cases that underwent a CVC replacement with "GWR" method with IF at our department between 2013 and 2023.

Utility of the web excision with pre-membranous incision for congenital intestinal atresia-type I and stenosis.

Purpose: This study analyzed the efficacy of web excision combined with a pre-membranous incision on the dilated proximal segment for congenital intestinal atresia with type I and stenosis (CIA-I/S).

Patients And Methods: Twenty-six patients underwent surgery for CIA-I/S from January 1990 to June 2022. Patients were categorized into 3 groups according to the surgical procedure: Group A, web excision with pre-membranous incision of the dilated intestine (n = 14); Group B, enteroplasty with a trans-membranous vertical incision (n = 7) and Group C, diamond-shaped anastomosis (n = 5).

Recent advancements in image-enhanced endoscopy in the pancreatobiliary field.

Image-enhanced endoscopy (IEE) has advanced gastrointestinal disease diagnosis and treatment. Traditional white-light imaging has limitations in detecting all gastrointestinal diseases, prompting the development of IEE. In this review, we explore the utility of IEE, including texture and color enhancement imaging and red dichromatic imaging, in pancreatobiliary (PB) diseases.

Time course of tumorigenesis of a newly developed sporadic hemangioblastoma in an elderly patient: illustrative case.

Background: von Hippel-Lindau disease-associated hemangioblastomas (HBs) account for 20%-30% of all HB cases, with the appearance of new lesions often observed in the natural course of the disease. By comparison, the development of new lesions is rare in patients with sporadic HB.

Observations: A 65-year-old man underwent clipping for an unruptured aneurysm of the anterior communicating artery.

Epididymitis with Pasteurella multocida isolated from two male Japanese Black beef calves.

Two male Japanese Black calves developed an enlarged scrotum and testis. Orchiectomy was performed and pus was collected during surgery. After removal of the testis, bacteriological and histopathological examinations were conducted to investigate the cause and confirm the diagnosis.

Surgical treatment of bovine nasal granuloma and an allergological exploration.

Nasal granuloma in cattle results from inflammation within, and attendant proliferation of, the nasal mucosa possibly in response to an allergic response. However, the relationship between nasal granuloma and allergies remains unclear. Furthermore, severe cases have a poor prognosis because there is currently no effective treatment.

Risk factors for catheter-related bloodstream infections in patients with intestinal failure undergoing home parenteral nutrition: a single-center study.

Purpose: The incidence and risk factors of catheter-related bloodstream infections (CRBSI) in patients with intestinal failure (IF) have not been established, partly because catheter management methods vary from different facilities. This study aimed to identify the risk factors and incidence rate of CRBSIs in patients with IF who were given prophylactic treatment.

Methods: Sixteen patients with IF who required home parenteral nutrition were enrolled in this study.

A novel in vivo model of ureteral fibrosis induced by calcium oxalate beads in C57BL/6J mice.

The global incidence of ureteroliths in humans is increasing, particularly posing a problem in developed countries. The most common stone type is calcium oxalate, which is associated with a high recurrence rate. In veterinary medicine, stones are the most common cause of ureteral obstruction in cats, accounting for 72-87% of cases.

Tip-in endoscopic papillectomy for ampullary adenoma near diverticulum to minimize complications.

Toyonaga and colleagues present a novel "tip-in endoscopic papillectomy" approach for resecting ampullary tumors, aiming to minimize complications like perforation and residual tumor by adapting the colonic polyp endoscopic mucosal resection tip-in method. The technique is described with accompanying video in a case of ampullary tumor near a diverticulum.