Publications by authors named "Ruonan Zou"
Article Synopsis
- Influenza poses a severe global health risk, with research uncovering unique microbial communities in the respiratory tract that could influence infection resistance.
- In mouse studies, transferring respiratory microbes from survivors of H9N2 influenza to antibiotic-treated mice improved their resistance to infection, particularly with higher levels of Aeromicrobium.
- Metabolomic analysis identified increased LysoPE (16:0) in mildly infected mice, which appears to enhance anti-influenza defenses by suppressing certain inflammatory markers, suggesting Aeromicrobium camelliae as a potential preventative agent for influenza.
The Acetic Acid Produced by Lactobacillus Species Regulates Immune Function to Alleviate PEDV Infection in Piglets.
Probiotics Antimicrob Proteins
March 2024
Porcine epidemic diarrhea virus (PEDV) infection results in significant mortality among newborn piglets, leading to substantial economic setbacks in the pig industry. Short-chain fatty acids (SCFA), the metabolites of intestinal probiotics, play pivotal roles in modulating intestinal function, enhancing the intestinal barrier, and bolstering immune responses through diverse mechanisms. The protective potential of Lactobacillus delbrueckii, Lactobacillus johnsonii, and Lactococcus lactis was first noted when administered to PEDV-infected piglets.
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