Improving Fuel Cell Performance of FeN-Based Catalysts by Introducing Graphitic Microdomains in the Carbon Matrix.

Breaking the known activity-stability trade-off is essential for the broad implementation of Fe-N-C catalysts in fuel cells. Here, we report the development of an atomically dispersed Fe-N-C catalyst with highly active FeN sites on carbon support with dispersed graphitic microdomains (FeN-Gmd), which were generated during the FeC-catalyzed graphitization. The introduction of graphitic microdomain makes the FeN-Gmd exhibit outstanding oxygen reduction reaction activity when used as a cathode catalyst in practical fuel cells, with impressive peak power densities of 1.

Efficacy of Three Amoxicillin Doses in Vonoprazan Dual Therapy for Helicobacter pylori Eradication: A Randomized Noninferiority Trial.

Background: Limited research has explored the efficacy of reduced amoxicillin dosages in vonoprazan-amoxicillin (VA) dual therapy for Helicobacter pylori eradication in China, and this study aimed to assess the noninferiority of these lower dosages compared to the standard high dose (3 g/d).

Methods: This was a noninferiority study with a -10% margin. H.

Clinical evaluation of personalized treatment guided by PCR detection from fecal samples: a real-world study.

Background: Growing antibiotic resistance in () diminishes eradication therapy effectiveness, emphasizing the need for accurate, non-invasive diagnostic techniques. This study aims to assess the clinical utility of PCR analysis of fecal samples for detecting antibiotic resistance in guiding personalized treatment for infection.

Methods: A retrospective, observational study was conducted across 13 hospitals within Jiangsu Province.

The impact of eradication with vonoprazan-amoxicillin dual therapy combined with probiotics on oral microbiota: a randomized double-blind placebo-controlled trial.

Background: infection and eradication have been reported to cause dysbiosis of the oral microbiota. Probiotics are increasingly being used to maintain the balance of the oral microbiota. We aimed to investigate the effects of infection, eradication with vonoprazan-amoxicillin dual therapy, and probiotics supplementation on the oral microbiota.