Fecal Calprotectin Combined with Blood Inflammatory Biomarkers Enhances Diagnostic Evaluation and Supports Mucosal Healing Assessment in Pediatric Crohn's Disease.

Purpose: Previous small-sample study suggested that fecal calprotectin (FC) combined with blood inflammatory biomarkers may aid in Crohn's disease (CD) diagnosis. This study aimed to validate the FC's diagnostic and mucosal healing assessment value of FC and a noninvasive composite index in pediatric CD.

Patients And Methods: Patients aged 2-17 years who underwent ileocolonoscopy for suspected or established CD were enrolled.