A prospective hospital-based study on C-reactive protein as a response predictor of antidepressant treatment in drug naïve patients with major depressive disorder.

Background: C-reactive protein (CRP) is an acute phase reactant that is implicated in the pathogenesis of major depressive disorder (MDD), due to its role in the execution of various important neurological events, including neurogenesis, mediation of neural plasticity, and synaptic transmission.

Aims: This study was conducted to determine the relationship between the level of CRP to remission rates after antidepressant therapy.

Methods: Fifty patients of first episode MDD with no past history of antidepressant exposure and other medical comorbidity were recruited after obtaining consent for Escitalopram therapy.

A Prospective Observational Study on Changes in Intraocular Pressure and Iridocorneal Angle Following the Use of Escitalopram and Amitriptyline.

Background: Depression has emerged as one of the prime morbidities affecting professional and personal lives worldwide. Antidepressants are one of the mainstays of management of depressive episodes. Although antidepressants are considered a safe class of drugs, the studies examining the effects of antidepressant prescription on intraocular pressure (IOP) have shown a propensity to increase IOP, but not consistently.

Medication adherence in bipolar disorder: Exploring the role of predominant polarity.

Objectives: Medication non-adherence is one important reason behind sub-optimal outcome from treatment of bipolar affective disorder (BPAD). Though various reasons behind medication non-adherence have been identified, little is known about the medication adherence patterns across various predominant polarities (PP) in BPAD.

Methods: 100 euthymic patients of BPAD were purposively recruited and the PP were determined.

Validation of revised reading the mind in the eyes test in the Indian (Bengali) population: A preliminary study.

Background: Social cognition deficits are common in clinical populations but there is a dearth of standardized social cognition assessment tools in India. Theory of mind (ToM) is an important aspect of social cognition which is often assessed with the revised reading the mind in eyes test (RMET-R). However, we do not have a statistically validated version of the test for the Indian population.

Has loneliness and poor resilient coping influenced the magnitude of psychological distress among apparently healthy Indian adults during the lockdown? Evidence from a rapid online nation-wide cross-sectional survey.

Background: The burden of psychological distress is increasing with the spread of the pandemic and also with the enforcement of its containment measures. The aim of this research was to determine the proportion of self-reported psychological distress, loneliness and degrees of resilient coping, and to also investigate the relationship of loneliness, coping and other variables with psychological distress among apparently healthy Indians during nation-wide lockdown period.

Methods: A cross-sectional, region-stratified survey using pre-designed pre-tested Google form disseminated via different social media platforms was conducted.

Correlates of insomnia among the adults during COVID19 pandemic: evidence from an online survey in India.

Background: Psychosocial distresses are often associated with sleep disorders. This is found as a common population level observation during natural calamities or emergency situations like a pandemic. The current study was conducted to determine the magnitude of self-reported insomnia, and to identify its associated factors among the apparently healthy Indian adult population having access to social media during the lockdown period of COVID 19 pandemic.

Storage, Degradation, and New Connectivity of Face-Related Semantic Memory in Alzheimer's Disease.

Background: Excepting amnesia, impairment of other domains also hampers the activity of daily living in Alzheimer's disease (AD). Although prosopagnosia poses problem in interacting with other persons, it rarely causes problem during interaction with close relatives as known voice acts as cue for recognition.

Objective: In a cohort of AD, we planned to study errors in recognition, naming, and assigning relationship of close relatives, to assess the type and frequency of errors and to explain with current knowledge and hypothesis.