Clinicopathological features of Lynch syndrome pedigrees with MSH2 c.351G>A gene variant.

Background: Lynch syndrome (LS) is an autosomal-dominant disorder that increases the risk of many cancers. To identify novel or rare pathogenic variants of MMR genes associated with LS, especially in Chinese pedigrees.

Methods: One four-generation Chinese Han family from northeast China with 29 members was enrolled.

High-Efficiency Photo-Fenton-like Catalyst of FeOOH/g-CN for the Degradation of PNP: Characterization, Catalytic Performance and Mechanism Exploration.

The composite photocatalyst FeOOH/g-CN was prepared through thermal polycondensation and co-precipitation methods, followed by XRD, SEM and UV-vis characterization. The stability of FeOOH/g-CN was explored by the recycling test. The active species in the reaction system were investigated by the capture experiment.

SP1-mediated up-regulation of lncRNA TUG1 underlines an oncogenic property in colorectal cancer.

The long non-coding RNA (lncRNA) taurine up-regulated gene 1 (TUG1) acts as tumor-promoting factor in colorectal cancer (CRC). We aimed to elucidate the mechanism by which the transcription factor specificity protein 1 (SP1) regulates TUG1 and microRNAs (miRs)/mRNAs in the context of CRC, which has not been fully studied before. Expression patterns of TUG1 and SP1 were determined in clinical CRC samples and cells, followed by identification of their interaction.

Optimization and Degradation Mechanism of Photocatalytic Removal of Bisphenol A Using Zn Fe S Synthesized by Microwave-assisted Method.

The sulfide photocatalyst of Zn Fe S was successfully synthesized by a facile microwave-assisted method, and Zn Fe S photocatalysts were characterized using SEM, EDX, XRD and BET. The specific surface area of synthesized Zn Fe S is 78.1 m g , and total pore volume is 0.