Evaluation of OPTOS wide-field fundus image projections for radiotherapy planning of uveal melanoma.

Purpose: To investigate the relationship between the stereographic and azimuthal equidistant projection (AEP) of the human retina for radiotherapy planning with OPTOS optomap wide-field fundus images (Optos, UK). Further, the geometric accuracy of an OPTOS fundus image is quantified.

Methods: The fundamental relationship between both projection modes was applied to transform images acquired with an OPTOS Silverstone camera to the azimuthal equidistant projection using MATLAB.

10 kHz cervical SCS for chronic neck and upper limb pain: 12 months' results.

Objective: Spinal Cord Stimulation (SCS) overlaps painful areas with paresthesia to alleviate pain. Ten kHz High-Frequency SCS (HF10 cSCS) constitutes a treatment option that can provide pain relief without inducing paresthesia. In this retrospective, open-label study, we evaluated the efficacy of HF10 cSCS in chronic neck and/or upper limb pain.

Patterns of proton therapy use in pediatric cancer management in 2016: An international survey.

Purpose: To facilitate the initiation of observational studies on late effects of proton therapy in pediatric patients, we report on current patterns of proton therapy use worldwide in patients aged less than 22 years.

Materials & Methods: Fifty-four proton centers treating pediatric patients in 2016 in 11 countries were invited to respond to a survey about the number of patients treated during that year by age group, intent of treatment, delivery technique and tumor types.

Results: Among the 40 participating centers (participation rate: 74%), a total of 1,860 patients were treated in 2016 (North America: 1205, Europe: 432, Asia: 223).

The delineation of target volumes for radiotherapy of lung cancer patients.

Purpose: Differences in the delineation of the gross target volume (GTV) and planning target volume (PTV) in patients with non-small-cell lung cancer are considerable. The focus of this work is on the analysis of observer-related reasons while controlling for other variables.

Methods: In three consecutive patients, eighteen physicians from fourteen different departments delineated the GTV and PTV in CT-slices using a detailed instruction for target delineation.

Scanning tropospheric ozone and aerosol lidar with double-gated photomultipliers.

The Ozone Profiling Atmospheric Lidar is a scanning four-wavelength ultraviolet differential absorption lidar that measures tropospheric ozone and aerosols. Derived profiles from the lidar data include ozone concentration, aerosol extinction, and calibrated aerosol backscatter. Aerosol calibrations assume a clear air region aloft.

Relationship of Somatic Cell Count and Total Sulfhydryls in Milk.

Individual milk samples from 32 cows were analyzed to determine the relationship between somatic cell concentration and total sulfhydryl concentration (cysteine plus reduced cystine). A significant relationship was detected between somatic cell count, which ranged from 1.7 × 10 to 1.