New Isolates of Betachloroviruses Shed Light on the Diversity and Biological Complexity of an Unexplored Group of Giant Algal Viruses.

The majority of giant algal viruses belong to the family , class , phylum . Among them, the genus is the most studied, with three recognized groups based on genomics and host range, although many fundamental questions remain to be elucidated, particularly regarding their diversity. In this study, we focus on betachloroviruses, a poorly explored subgroup that infects the alga Pbi.

Follow-up imaging characteristics of a Novel Braided Stent (BosSTENT™) in treating transverse sinus stenosis related to venous congestion and/or pulsatile tinnitus.

BackgroundTransverse sinus stenosis (TSS) is increasingly recognized as a key contributor to pulsatile tinnitus (PT) and cerebral venous congestion (CVC), including idiopathic intracranial hypertension (IIH). While venous stenting has shown promising clinical outcomes, long-term imaging data on dedicated braided stents remain limited.ObjectiveTo report the clinical and imaging outcomes of the BosSTENT™, a novel self-expanding braided stent, in patients with symptomatic TSS.

Revealing the hidden diversity of Chlorella heliozoae-infecting giant viruses.

A new level of viral complexity has emerged from the isolation of green algae-infecting chloroviruses from diverse aquatic environments around the world over the past few decades. This study focuses on describing and comparing the genomic features of gammachloroviruses, previously referred to as SAG-viruses. We present 24 novel isolates capable of forming plaques on lawns of Chlorella heliozoae SAG 3.

Vacuum ultraviolet spectroscopy of pyrimidine derivatives: the effect of halogenation.

As a prototypical molecule in the important class of halopyrimidines, 2-chloropyrimidine has been the subject of numerous spectroscopic studies. However, its absorption spectrum under vacuum ultraviolet (VUV) radiation has not yet been reported. Here, we close this gap by presenting high-resolution VUV photoabsorption cross-sections in the 3.

Case Report of Management of Fowler's Syndrome During Pregnancy: Challenges and Outcomes.

Fowler's syndrome (FS) is a rare cause of urinary retention affecting young women, characterized by dysfunctional urethral sphincter relaxation. Its management during pregnancy presents challenges, particularly regarding sacral neuromodulation (SNM), which is the preferred treatment but remains controversial due to concerns about uterine contractions and limited safety data. Intermittent catheterization is an alternative but increases the risk of urinary tract infections and pregnancy complications.

Investigations into the Diversity and Distribution of tRNA and Phylogenetics of Translation Factors in Amoebozoa-Infecting .

Translation is a sine qua non process for life as we know it. Translation factors (TFs) and tRNAs are rare among viruses but are commonly found in giant viruses of the class . In this study, we explored the diversity and distribution of tRNAs in giant viruses that were isolated and replicated in amoebae (phylum Amoebozoa), and investigated the evolutionary history of TFs to gain insights into their origins in these viruses.

Assessment of mortality due to severe SARS-CoV-2 infection in public and private intensive care units in Brazil: a multicenter retrospective cohort study.

Background: This retrospective multicenter cohort study compared characteristics and outcomes of 5,790 critically ill patients with COVID-19 in Brazil's public and private intensive care units. Patients in public intensive care units exhibited greater disease severity, more frequent use of organ support, and higher mortality rates compared to those in private intensive care units. The risk of in-hospital death was more than twice as high in public intensive care units.

Association between agenesis of permanent teeth and other dental anomalies in nonsyndromic patients: Systematic review.

Background: Most cases of tooth agenesis are presented in the form of hypodontia with different patterns of missing teeth. In addition, there is a frequent clinical association between tooth agenesis and other anomalies.

Objective: To systematically analyze the literature on the prevalence of agenesis of permanent teeth associated with other dental anomalies in nonsyndromic patients.

A nickel glutamate metal biomolecule framework.

This paper describes the synthesis of a MbioF (Metal-biomolecule Framework) using glutamic acid and nickel carbonate as precursors. The direct action of glutamic acid (HGlu) on basic nickel carbonate (NiCO·2Ni(OH)·4HO) initially indicated the formation of a complex, [Ni(HGlu)], which was then treated in a Teflon-lined stainless steel autoclave at 100 °C for 24 hours, resulting in the compound {[Ni(Glu)(HO)]·HO}, with a yield of 43%. The resolution of the structure of this compound by single-crystal X-ray diffraction indicated that it belongs to the orthorhombic crystal system and space group 222, with a structure analogous to those of the compounds {[Co(Glu)(HO)]·HO}, {[Cu(Glu)(HO)]·HO} and {[Zn(Glu)(HO])·HO} described in the literature, with a molecular formula of CHNONi·HO, molar mass of 239.

DFT investigation of green stabilizer reactions: curcumin in nitrocellulose-based propellants.

Context: Nitrocellulose, widely used in energetic materials, is prone to thermal and chemical degradation, compromising safety and performance. Stabilizers are molecules used in the composition of nitrocellulose-based propellants to inhibit the autocatalytic degradation process that produces nitrous gases and free nitric acids. Curcumin, (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, known for its antioxidant properties and a potential green stabilizer, was investigated using Density Functional Theory (DFT) focusing on its interaction with nitrogen dioxide.

Changes in salivary biomarkers of pain, anxiety, stress, and inflammation related to tooth movement during orthodontic treatment: a systematic review.

Objective: This systematic review aimed to analyze the literature on changes in endogenous salivary biomarkers of pain, anxiety, stress, and inflammation related to tooth movement during orthodontic treatment of children and adolescents.

Material And Methods: An electronic search was performed in nine databases to identify quasi-experimental studies, without restricting publication language and year. Two reviewers extracted the data and assessed the individual risk of bias using the JBI tools, and the certainty of evidence using the GRADE tool.

Activation of the three deltoid muscle portions during common strengthening exercises: A systematic review.

Background: The three portions of the deltoid muscle (anterior, middle, and posterior) are primary movers of several strengthening exercises and their contribution to different exercises can be measured using surface electromyography.

Purpose: To systematically review studies that evaluated the activation of commonly used exercises and their variations.

Methods: A search was conducted in PubMed (MEDLINE), Web of Science, Scopus and SciELO.

Sex-differences in neuromuscular control of hip abductors during isometric submaximal tasks.

Background: One key focus in the literature is the need to better understand how males and females perform neuromuscular control, which requires consideration of muscle morphology, as it may change neural drive during force production. Although previous studies focused on muscles around the knee and ankle, it is crucial to explore the behavior of other muscles, such as the hip abductors, since many lower limb conditions more common in females have been associated with alterations in hip muscles.

Research Questions: Are electromyography (EMG) variables (amplitude and low- and high frequency bands) of hip abductors during submaximal isometric tasks different between males and females? How is muscle size associated with EMG responses during these tasks?

Methods: Thirty-six participants (males, n = 18; females, n = 18) had muscle and subcutaneous thickness of gluteus medius (GMed) and tensor fascia latae (TFL) measured.

Risk of psychiatric hospitalization in low-income youth: longitudinal findings from the 100 Million Brazilian Cohort.

Background: Youth psychiatric hospitalizations have been associated with negative outcomes, including premature death and post-discharge self-harm. Identifying risk factors for youth psychiatric hospitalization is crucial for informing prevention strategies. We aimed to evaluate the risk factors for psychiatric hospitalizations among low-income youth in Brazil.

Different neuromuscular parameters are associated with knee abduction and hip adduction angles during functional tasks.

Knee abduction and hip adduction during functional tasks may indicate increased joint injury risk and discriminate between pathological and healthy people. Muscles' neuromuscular variables such as amplitude (EMG) and onset (EMG) have been used to explain kinematics. The study aimed to evaluate the correlation between two EMG variables of seven trunk and lower limb muscles and 3D kinematics during two tasks.

Genomics and evolutionary analysis of infecting viruses demarcate criteria for defining species of giant viruses.

Chloroviruses exhibit a close relationship with their hosts with the phenotypic aspect of their ability to form lytic plaques having primarily guided the taxonomy. However, with the isolation of viruses that are only able to complete their replication cycle in one strain of , systematic challenges emerged. In this study, we described the genomic features of 53 new chlorovirus isolates and used them to elucidate part of the evolutionary history and taxonomy of this clade.

Accuracy of the Dual Path Platform (DPP) rapid test for the diagnosis of leptospirosis: A multi-center study in six Brazilian states.

Leptospirosis is a zoonotic disease with significant global impact and a challenging diagnosis. The utilization of adequately validated rapid tests is relevant for the opportune identification of the disease and for reduction in fatality rates. The present study analyzes the accuracy and reliability of the Dual Path Platform (DPP) assay -produced in Brazil by the Oswaldo Cruz Foundation (Fiocruz)- for diagnosing leptospirosis.

Pristine helium from the Karoo mantle plume within the shallow asthenosphere beneath Patagonia.

Mantle xenoliths usually represent fragments derived from the depleted and degassed lithospheric mantle with He/He isotope ratios (6 ± 1 R) lower than those of mid-ocean ridge basalts (8 ± 1 R). Otherwise, basalts from oceanic islands related to hotspots often have high He/He ratios (>10 R), suggesting a deep and pristine undegassed mantle source. Here we present a striking high-He/He component (up to 27.

Experimental and Theoretical Study on Electron Ionization and Fragmentation of Propylene Oxide─the First Chiral Molecule Detected in the Interstellar Medium.

Propylene oxide, CHCHOCH, is the first chiral molecule detected in space and the third C3 oxide detected toward the Sagittarius B2 (Sgr B2 (N)) molecular cloud, the others being propanal, CHCHCHO, and acetone, (CH)CO. With homochirality being ubiquitous in the building blocks of living matter, the formation and decay paths of propylene oxide in space are of specific interest. Motivated by the significant role of photo- and secondary electrons in astrochemistry, we have studied electron ionization and fragmentation of propylene oxide.

A taxonomic proposal for cedratviruses, orpheoviruses, and pithoviruses.

Orpheoviruses, cedratviruses, and pithoviruses are large DNA viruses that cluster together taxonomically within the order Pimascovirales of the phylum Nucleocytoviricota. However, they were not classified previously by the International Committee on Taxonomy of Viruses (ICTV). Here, we present a comprehensive analysis of the gene content, morphology, and phylogenomics of these viruses, providing data that underpinned the recent proposal to establish new taxa for their initial classification.

The genomic and phylogenetic analysis of raises questions about the evolution of Marseilleviridae lineages and their taxonomical organization.

Unlabelled: Marseilleviruses (MsV) are a group of viruses that compose the Marseilleviridae family within the Nucleocytoviricota phylum. They have been found in different samples, mainly in freshwater. MsV are classically organized into five phylogenetic lineages (A/B/C/D/E), but the current taxonomy does not fully represent all the diversity of the MsV lineages.