Cutaneous Rosai-Dorfman Disease Mimicking Granulomatous Dermatoses: A Rare Case Report.

Cutaneous Rosai-Dorfman disease (CRDD) is a rare non-Langerhans cell histiocytosis that mimics various granulomatous and neoplastic dermatoses, often leading to misdiagnosis. We report an 18-year-old male with a 13-year history of progressively enlarging erythematous plaques over the nasal bridge and right forearm, initially diagnosed as granulomatous inflammation. Histopathological examination revealed emperipolesis only after meticulous serial sectioning, and immunohistochemistry confirmed the diagnosis of CRDD.

An unusual case of inflammatory linear verrucous epidermal nevus on the labia majora.

Inflammatory linear verrucous epidermal nevus (ILVEN) is a variant of keratinocytic epidermal nevi. In contrast to noninflammatory epidermal naevi, ILVEN is less common, typically erythematous, and persistently pruritic. It usually appears at birth or in early childhood and follows a linear distribution along Blaschko's lines.

A case of vulvar bowenoid papulosis.

Bowenoid Papulosis (BP) is an uncommon, Human Papillomavirus (HPV) induced genital dysplasia, usually observed in younger, sexually active individuals. We report a case of a 37-year-old woman who presented with dark, itchy lesions over her external genitalia of 6 months duration. Clinical examination and histopathological evaluation confirmed the diagnosis of BP.

Role of serum interleukin-19 (IL-19) levels in acne vulgaris: a comprehensive case control study.

Acne vulgaris (AV) has a multifactorial pathogenesis, with inflammation being a key factor. The pro-inflammatory role of interleukin (IL)-19 has been explored in several systemic and some dermatological conditions. This study aimed to analyse serum levels of IL-19 in cases as well as healthy controls and to assess its correlation with the disease severity.

Granulomatous vulvitis complicated by polymicrobial growth.

Granulomatous vulvitis (GV) is a rare chronic inflammatory condition presenting with persistent vulvar swelling and noncaseating granulomas, often mimicking Crohn's disease and sarcoidosis. We report a 21-year-old sexually inactive woman with a five-month history of painless vulvar swelling and occasional itching, complicated by secondary polymicrobial infection. A thorough evaluation excluded other granulomatous diseases, and histopathology revealed noncaseating granulomas, supporting the diagnosis of granulomatous vulvitis.

Are antibiotics still relevant in acne? A review of the therapeutic conundrum.

Antibiotics have constituted the mainstay of acne therapy despite acne being classified as an inflammatory disorder. The indiscriminate usage of antibiotics over the years has thus fueled the issue of antimicrobial resistance. Cutibacterium acnes (C.