Silver nanoparticles enhance chilli resistance against Colletotrichum capsici through dual antifungal and immunity-inducing mechanisms.

Background: Conventional pesticides pollute the environment by contaminating water reservoirs with harmful residues. This study investigated the potential of silver nanoparticles (AgNPs) to treat Colletotrichum capsici-induced anthracnose disease in chilli plants. By leveraging the unique chemical and physical characteristics of AgNPs, we evaluated their antifungal efficacy and their roles in boosting plant immunity.

Bacillus velezensis and Zinc Oxide Nanoparticles in Suppressing Colletotrichum capsici-Induced Anthracnose Disease in Chili: Mechanistic Insights Into Antioxidant System and Plant Growth.

The effectiveness of Bacillus velezensis and zinc oxide nanoparticles (ZnONPs) as potential treatments to control fungal infection in chili peppers was investigated. We conducted greenhouse trials involving inoculation alongside in vitro tests. Plants were inoculated either with ddHO (control), Colletotrichum capsici (CC), Bacillus velezensis (BV), zinc oxide nanoparticles (ZnONPs), or combination BV + ZnONPs (BZC).

A comprehensive review of integrated management strategies for damping-off disease in chili.

Damping-off disease in chili ( L.) cultivation is a significant global issue, severely affecting seeds, seedlings, and young plants, regardless of the location of cultivation, whether in greenhouses or open fields. Despite chili being a widely popular vegetable used in various cuisines globally, farmers face challenges in meeting the growing demand due to the extensive damage caused by this disease, ranging from 20 to 85%.

Novel chiral phthalimides: Antimicrobial evaluation and docking study against Acinetobacter baumannii's OmpA protein.

Antibiotics have been a vital component in the fight against microbial diseases for over 75 years, saving countless lives. However, the global rise of multi-drug-resistance (MDR) bacterial infections is pushing us closer to a post-antibiotic era where common infections may once again become lethal. To combat MDR Acinetobacter baumannii, we investigated chiral phthalimides and used molecular docking to identify potential targets.

Chiral phthalimides against penicillin-binding protein 2a of methicillin-resistant : molecular docking and analysis.

() is a commensal bacterium and an opportunistic pathogen causing a wide variety of infections ranging from localized skin and soft tissue infections to life-threatening severe bacteremia, osteomyelitis, endocarditis, atopic dermatitis, prosthetic joint infection, staphylococcal food poisoning, medical device-related infections, and pneumonia. It is attributed to an acquired resistant gene, , encoding penicillin-binding protein 2a (PBP2a). PBP2a is an essential protein responsible for the resistivity of methicillin-resistant (MRSA) to various beta-lactam antibiotics.

Molecular docking and in vitro antibacterial activity of chiral phthalimide on ESBL producing gram negative bacteria.

Antibiotic resistance is tricky enemy that challenges our healthcare system. It is a stealthy, adaptive and ever evolving opponent, which can take years to develop but can spread like wildfire. In this study, derivatives of chiral phthalimides were developed with this aim to control the growth of resistant strains of Klebsiella pneumonia, Escherichia coli and Pseudomonas aeruginosa by targeting their resistance causing proteins and explore their binding interaction focal points through computational docking.