Valorization of agri-food crucifer vegetables waste for food, functional food and nutraceuticals applications.

Valorization of food byproducts, especially fruits and vegetables, has recently attracted considerable attention, mostly due to their high wastage rates. Exploitation of these byproducts, including the non-edible parts of crucifer vegetables, may provide value-added opportunities in the food, functional food, and nutraceutical industries as well as in non-food applications such as therapeutics, biofuels, and paper pulp production. This review focuses on the state-of-the-art valorization practices of crucifer vegetable agro-food wastes including those of broccoli, cauliflower, cabbage, kale, Brussels sprouts, collards, watercress and radish constituting the main cultivated crucifer vegetables worldwide and suggests potential novel uses through upcycling.

Nifuroxazide-loaded cubosomes exhibit an advancement in pulmonary delivery and attenuate bleomycin-induced lung fibrosis by regulating the STAT3 and NF-κB signaling: A new challenge for unmet therapeutic needs.

Pulmonary fibrosis (PF) is a chronic progressive disease that portends a very poor prognosis. It has been suggested that STAT3 is a potential target in PF. This study highlights the importance of cubosomes as a drug delivery system in enhancing the bioavailability of nifuroxazide (NXZD), a poorly soluble STAT3 inhibitor.