Publications by authors named "Rebecca Seidemann"

Hyperactivation of amygdala is a neural marker for post-traumatic stress disorder (PTSD) and improvement in control over amygdala activity has been associated with treatment success in PTSD. In this randomized, double-blind clinical trial we evaluated the efficacy of a real-time fMRI neurofeedback intervention designed to train control over amygdala activity following trauma recall. Twenty-five patients with PTSD completed three sessions of neurofeedback training in which they attempted to downregulate the feedback signal after exposure to personalized trauma scripts.

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Emotional numbing symptoms are a core aspect of posttraumatic stress disorder (PTSD). Since the initial characterization of PTSD in DSM-III, emotional numbing symptoms have been revised and grouped under different symptom clusters (avoidance in DSM-IV, negative alterations in cognitions, and mood in DSM-5). Previous studies have found emotional numbing symptoms to be associated with greater PTSD severity, functional impairment, and worse treatment outcomes.

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Article Synopsis
  • PTSD is a common and debilitating condition, but its impact on reward functioning, particularly through the lens of anhedonia, remains under-researched.
  • Most past research has mainly focused on fear-related aspects of PTSD, such as fear learning and extinction.
  • The review calls for more studies to explore how trauma influences the reward system, as this knowledge gap could be hindering advances in PTSD treatment.
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