Idiopathic Acute Exudative Polymorphous Vitelliform Maculopathy - Case Series and Extended Features.

Purpose: Idiopathic acute exudative polymorphous vitelliform maculopathy (AEPVM) is a rare condition characterized by acute vision loss and distinctive retinal findings. Here we describe the disease course in three previously unpublished subjects diagnosed with AEPVM and a previously undescribed imaging feature.

Methods: We present the clinical presentation, disease progression, and multimodal imaging, along with retinal electrophysiology and genetic testing for PRPH2 and BEST1.

A seven-year electroretinography follow-up of a patient with melanoma-associated retinopathy stabilized on pembrolizumab treatment.

Purpose: Melanoma-associated retinopathy (MAR) is a rare, auto-immune paraneoplastic syndrome associated with metastatic melanoma. Over the last decade, patient survival has improved dramatically, mainly due to the development of immunotherapy. However, data on long-term MAR patient follow-up and response to modern standard-of-care treatment are lacking.