Publications by authors named "Rayan A Siraj"

Anxiety and depression are common comorbidities in patients with chronic obstructive pulmonary disease (COPD), which can contribute to increased morbidity, reduced quality of life, and worse clinical outcomes. Nevertheless, these psychological conditions remain largely overlooked. This narrative review includes studies published between 1983 and 2025 to synthesise the current evidence on the risk factors, clinical impacts, and therapeutic strategies for these comorbidities.

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Background: Stroke represents a significant global health issue, consistently identified as one of the leading causes of disability and mortality worldwide. Smoking constitutes a major risk factor for stroke development.

Objectives: This study evaluated the prevalence of smoking among stroke patients in Saudi Arabia.

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: Stroke is a common and fatal condition impacting millions worldwide. Understanding the risk factors, symptoms, and consequences at an earlier stage, specifically in highly at-risk populations such as smokers, is crucial for mitigating the stroke burden. : A cross-sectional study was conducted in Saudi Arabia on more than 1000 smokers.

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Background: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder characterized by persistent inflammation and airflow limitation. The ketogenic diet (KD), recognized for its anti-inflammatory properties, has potential therapeutic benefits for COPD management. However, healthcare professionals' perceptions of KD's efficacy and applicability in COPD care remain underexplored, particularly in Saudi Arabia.

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The purpose of this research is to compare and contrast the application of machine learning and deep learning methodologies such as a dual-branch convolutional neural network (CNN) model for detecting obstructive sleep apnea (OSA) from electrocardiogram (ECG) data. This approach solves the limitations of conventional polysomnography (PSG) and presents a non-invasive method for detecting OSA in its early stages with the help of AI. The research shows that both CNN and dual-branch CNN models can identify OSA from ECG signals.

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Background: Chronic obstructive pulmonary disease (COPD) significantly contributes to global morbidity and mortality. Despite increasing COPD prevalence in Saudi Arabia, knowledge of and barriers to adherence to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines among respiratory therapists (RTs) remain limited. This study assessed RT awareness and barriers to adherence to the updated 2023 GOLD guidelines for COPD management in Saudi Arabia.

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Objective: Cognitive impairment is a common comorbidity, yet overlooked, in patients with chronic obstructive pulmonary disease (COPD). However, little is known about the current practice and perceptions of physicians on recognising and managing cognitive impairment in patients with COPD in Saudi Arabia. This study aimed to investigate current practices and perceptions of physicians in Saudi Arabia regarding the recognition and management of cognitive impairment in COPD patients.

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: Despite the significant impacts of cognitive impairment on patients with chronic obstructive pulmonary disease (COPD), there is limited information available on healthcare workers' (HCWs) perceptions, current practice, and barriers to managing COPD patients with cognitive impairment. : A cross-sectional questionnaire was distributed to HCWs in Saudi Arabia between April and December 2023. The collected responses were analysed using descriptive statistics and logistic regression models.

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Background: There is a limited data examining the practice of using the airway pressure release ventilation mode for patients with acute respiratory distress syndrome among respiratory therapists.

Objectives: To evaluate the current practice and barriers when using airway pressure release ventilation mode in the management of patients with acute respiratory distress syndrome.

Methods: A cross-sectional online survey was disseminated between November 2022 and April 2023 to respiratory therapists in Saudi Arabia.

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Article Synopsis
  • The study investigates the preferences and clinical practices of physicians in Saudi Arabia regarding airway clearance devices for managing chronic obstructive pulmonary disease (COPD).
  • A survey conducted with 445 physicians revealed that most prefer Flutter and Acapella devices, but 12.6% were unfamiliar with any device.
  • Despite the preferences, there is a notable lack of prescribing history for these devices, indicating a need for increased awareness and integration into COPD treatment practices.
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Objectives: The objective of this study is to examine the hospitalisation profile for respiratory diseases in Australia between 1998 and 2019.

Design: An ecological study.

Setting: A population study that involved all private and public hospitalisations for respiratory diseases in Australia from 1998 to 2019.

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Article Synopsis
  • * A study conducted at King Khalid University Hospital in Saudi Arabia from July to December 2023 found that 72.1% of asthma patients were overweight or obese, with higher BMI in females compared to males.
  • * The study also indicated that a greater percentage of obese female asthma patients (38.21%) had comorbidities compared to male patients (24.14%), highlighting the need for focused strategies to address these health issues in this population.
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Background: Nursing instructors play an important role in improving the clinical experience of nursing students. Despite this, little is known about the characteristics of effective clinical instructors.

Objective: Identifying the perceptions of nursing students, faculty, and preceptors of effective clinical instructors.

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Background: Loneliness poses significant public health concerns on a global scale. Being alone and lacking social connections have been proven to impact prognosis and response to treatment in different diseases, including COPD. Yet, the prevalence and burden of loneliness on COPD outcomes remain unclear.

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Introduction: Imposter syndrome is common among health disciplinary students, leading to serious consequences. However, the impact of imposter syndrome on self-esteem and quitting intention among respiratory therapy students has not been well researched.

Objective: To report on the prevalence of imposter syndrome and assess its impacts on self-esteem and quitting intention among respiratory therapy students in Saudi Arabia.

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Background: Night shift duties are crucial in the ICU to ensure care continuity, where critically ill patients require round-the-clock care. However, cumulative night shift duties may disturb circadian rhythm, insomnia, fatigue, and depression, and require further elucidation.

Objectives: This study aims to examine the negative consequences of various night shift patterns on insomnia, fatigue, and mental health of ICU Workers.

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Background: Nonadherence to therapies and psychological disorders are associated with poor asthma control. This study aims to assess the prevalence of anxiety and depressive symptoms, asthma control, and adherence to inhalers and to investigate whether there is an association of anxiety and depressive symptoms with adherence to inhalers and asthma control.

Methods: We measured anxiety and depressive symptoms using the Hospital Anxiety and Depression Scale in patients with asthma.

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Background: High-flow nasal cannula (HFNC) is an essential non-invasive oxygen therapy in acute respiratory distress syndrome (ARDS) patients. Despite its wide use, research assessing the knowledge, practice, and barriers to using HFNC among respiratory therapists (RT) is lacking.

Methods: A cross-sectional questionnaire was conducted among RTs in Saudi Arabia between December 19, 2022, and July 15, 2023.

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Background: Tobacco smoking is one of the most significant health-related problems worldwide. However, the prevalence and sociodemographic determinants of tobacco and nicotine use among students on healthcare courses in Saudi Arabia are limited.

Methods: This cross-sectional study used a questionnaire that was distributed via SurveyMonkey between November 2022 and June 2023 to all student universities offering healthcare courses.

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Background: Lung cancer is currently the most fatal form of cancer worldwide, ranking as the fourth most prevalent type in Saudi Arabia, particularly among males. This trend is expected to increase with growing population, lifestyle changes, and aging population. Understanding the awareness of the Saudi population regarding the risk factors and symptoms of lung cancer is necessary to attenuate the predicted increase in cases.

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Background: Obesity is a common cause of dyspnea. However, the impacts of obesity on spirometry parameters, particularly among individuals with unexplained dyspnea, have not been well investigated.

Objectives: This study aimed to explore the prevalence of overweight and different classes of obesity and their effect on spirometry parameters among subjects with unexplained dyspnea in Saudi Arabia.

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Background: Obesity is common among chronic obstructive pulmonary disease (COPD) patients and is associated with an increase in acute exacerbation episodes. However, data on obesity's impact on and association with clinical outcomes among patients with COPD are limited. This study aimed to determine overweight and obesity prevalence and associations with spirometry profiles, intensive care unit (ICU) admission, and comorbidities in patients with COPD.

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Background: Limited data is available on awareness and clinical management of the airway pressure release ventilation (APRV) mode of ventilation for acute respiratory distress syndrome (ARDS) patients among physicians who work at in adult critical areas. This study aimed to assess the knowledge and current practice of using APRV mode with ARDS patients and identify barriers to not using this mode of ventilation among physicians who work in adult critical areas in Saudi Arabia.

Methods: Between November 2022 and April 2023, a cross-sectional online survey was disseminated to physicians who work in adult critical areas in Saudi Arabia.

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Background: The issue of burnout syndrome among health discipline students is gaining heightened attention due to its serious effects, which causes them to have the intention to quit. Despite this, limited studies are available on the extent of burnout and its association with resilience and intention to drop out among clinical-level nursing students.

Objective: To explore the relationship between burnout, resilience, and intention to quit among nursing students.

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Article Synopsis
  • There is limited research on the knowledge and confidence of respiratory therapists (RTs) regarding the ask, advice, and refer (AAR) model for smoking cessation, prompting a study analyzing factors impacting their practices in Saudi Arabia.
  • Data collected from 206 RTs revealed a significant lack of tobacco-related knowledge, with many not having relevant certifications or attending related educational events, despite reporting high confidence in counseling.
  • Key predictors of RTs' tobacco counseling confidence included clinical experience, familiarity with cessation program information, and proactive inquiry and advice about smoking status, indicating that improving these areas can boost their effectiveness in using the AAR model.
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