Twenty-year trend of thyrotoxicosis and thyrotoxic periodic paralysis: a population-based cohort study.

Objective: Thyrotoxic periodic paralysis (TPP) is a rare but potentially lethal complication of thyrotoxicosis. Absence of large cohorts limits the conduct of epidemiology studies. We aimed to establish a population-based registry of thyrotoxicosis and TPP in Hong Kong, and evaluate their trend.