Parasitol Res
September 2025
Human toxocariasis presents in several forms, including visceral larva migrans, ocular larva migrans, covert toxocariasis, and neurotoxocariasis. Although several studies suggest a potential link between toxocariasis and epilepsy, this link is still debated. Additional mechanistic and experimental studies in animal models are essential for a better understanding of this association.
View Article and Find Full Text PDFActa Parasitol
April 2025
Purpose: Toxocara canis is a globally distributed zoonotic parasite found in dogs' intestines, leading to various pathological damages, particularly to the intestinal flora. The larval stage causes human toxocariasis, especially in children, and may result in neurological disorders and blindness. Quercetin is a flavonoid with strong secondary metabolites and possesses medicinal advantages and antiparasitic qualities.
View Article and Find Full Text PDFThe present study concerns the classification and morphologic features of species variously assigned to the genera Skrjabinotaenia Akhumyan, 1946 and Meggittina Lynsdale, 1953 (Cestoda: Cyclophyllidea: Catenotaeniidae), particularly those characterized by a widely divided testicular field. The latter feature together with the typical structure of the ovary and uterus give grounds for assigning Skrjabinotaenia oranensis (Joyeux & Foley, 1930), Meggittina baeri Lynsdale, 1953, M. cricetomydis (Hockley, 1961) and M.
View Article and Find Full Text PDFJ Exp Zool A Ecol Integr Physiol
April 2025
One neglected zoonotic illness is toxocariasis. There are not enough anthelmintic drugs in the market to treat low-effectiveness toxocariasis against migrating larvae. Therefore, it is critical to find new, safe alternatives to toxocariasis treatment today.
View Article and Find Full Text PDFJ Exp Zool A Ecol Integr Physiol
November 2024
Toxocariasis is a zoonotic parasitic infection with worldwide distribution and high impact on human health. It has a limited clinical resolution with the available drugs, making it challenging to treat. Quercetin, which possesses biological and pharmacological qualities including antiparasitic, antioxidant, and anticancer activities, is a possible substitute for the current medications.
View Article and Find Full Text PDFToxocariasis is a zoonosis that represents a serious threat to public health particularly in tropical and subtropical areas. Currently, albendazole, the most effective drug for treating visceral toxocariasis, shows moderate efficacy against the larvae in tissues and has some adverse effects. Artemether is an antiparasitic drug mainly used in the treatment of malaria and showed effectiveness against numerous helminthic infections.
View Article and Find Full Text PDFThere are currently insufficient anthelmintic medications available for the treatment of toxocariasis. For instance, Albendazole (ABZ) is the preferred medication, but its effectiveness against tissue-dwelling parasites is limited. In addition, Metformin (MTF) is a widely used oral antidiabetic medication that is considered to be safe for treatment.
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