Development and Application of an Assay to Evaluate the Anti-Parasitic Effect of Humoral Responses against .

Mounting a balanced and robust humoral immune response is of utmost importance for reducing the infectivity of . While the role of such a response in controlling the infection is well known, there is a lack of tools that can be used to quickly evaluate it. We developed a serum parasite inhibition assay (to evaluate changes in the parasite infection after exposing infective trypomastigotes to serum samples from infected patients).

An Overview of Current Uses and Future Opportunities for Computer-Assisted Design of Vaccines for Neglected Tropical Diseases.

Neglected tropical diseases are infectious diseases that impose high morbidity and mortality rates over 1.5 billion people worldwide. Originally restricted to tropical and subtropical regions, changing climate conditions have increased their potential to emerge elsewhere.