Evaluation of the accuracy and interobserver agreement of the reverse shoulder angle in the preoperative planning of reverse total shoulder arthroplasties.

Background: Differences in implant positioning between anatomical and reverse shoulder arthroplasties have raised concerns about the adequacy of assessing the global glenoid inclination (GGI) using the method described by Maurer to define the position of the metallic base in reverse shoulder arthroplasty. The reverse shoulder angle (RSA) has been proposed to measure the inclination of the lower half of the glenoid. This study aims to evaluate the interobserver agreement of manual measurements of the RSA using two-dimensional (2D) computed tomography (CT) images and its relationship with the automated measurement of the GGI.

Comparison of Manual Two-dimensional and Automated Three-dimensional Methods of Assessing Shoulder Joint Morphology through Computed Tomography Images.

 To evaluate the interobserver agreement in the measurement of anatomical parameters of the shoulder using manual methods of two-dimensional (2D) computed tomography (CT) unformatted in the plane of the scapula and to compare them with the automated measurement obtained through the Blueprint (Wright Medical, Memphis, TN, United States) software, which uses reconstructed three-dimensional (3D) images.  The present is a cross-sectional study in which 2D CT images of 38 patients with different diagnoses were used. The anatomical parameters were measured by the manual methods described by Friedman et al.

Three-dimensional kinematic evaluation of scapulohumeral rhythm after reverse shoulder arthroplasty: a systematic review and meta-analysis.

Background: The movement of the arm relative to the trunk results from 3-dimensional (3D) coordinated movements of the glenohumeral (GH) and scapulothoracic (ST) joints and dictates the scapulohumeral rhythm (SHR). Alterations in SHR increase joint overload and may lead to low functional scores, pain, and failures in patients undergoing reverse total shoulder arthroplasty (RSA). The goal of this systematic review and meta-analysis was to examine 3D SHR kinematics after RSA and compare it to that of asymptomatic shoulders.

Incidence and Risk Factors of the Complications Related to the Latarjet Surgery.

 The Latarjet procedure is a well-accepted treatment of shoulder instability. This technique is associated with a unique set of complications with overall rates of up to 30%. The purpose of the present study was to investigate the incidence and risk factors associated with complications after open Latarjet procedure.

Treatment of chronic locked posterior dislocation of the shoulder with the modified McLaughlin procedure.

Background: Locked posterior dislocation of the shoulder (LPDS) is a challenging condition for the orthopedic surgeon. The problem with cases of chronic LPDS is that they may result in worse clinical outcomes because the size of the reverse Hill-Sachs lesion and cartilage damage can increase over time. Multiple treatment strategies have been reported in the literature for the treatment of chronic cases.

Arthroscopic Fixation of a Large Osteochondral Fragment From the Glenoid After First Episode Dislocation.

Osteochondral lesions of the glenoid are not so uncommon after traumatic cases of shoulder dislocation and can be a challenge to the shoulder surgeon because of the technical difficulty and the potential to progression to shoulder arthritis. An all-arthroscopic technique of fixation of a large osteochondral fragment is used to allow optimal visualization and reduction, minimize the morbidity of the open approach, and provide good functional results.

Dietary breadth of the animal protein consumed by riverine communities in the Tapajós National Forest, Brazil.

In small-scale human settlements, the acquisition of animal protein is strictly related to subsistence activities, and yours dietary habits are determined by the availability and the selectivity permitted by the diversity of these resources. This study analyzed the consumption of animal protein sources in seven traditional riverine communities of the Tapajos National Forest, located in Eastern Brazilian Amazonia, considering fish, game meat and domestic animals. The analysis of animal protein consumption was based on the assumptions of the diet breadth model and the Optimal Foraging Theory.

Lack of kinin B₁ receptor potentiates leptin action in the liver.

Kinins B1 and B2 receptors (B1R and B2R) are classically associated with inflammation, but our group has recently demonstrated new roles for B1R in metabolism using a knockout model (B1 (-/-)). B1 (-/-) mice display improvement on leptin and insulin sensitivity and is protected from high fat diet (HFD)-induced obesity. Here, we evaluate the hepatic effects of the B1R ablation and its role on hepatic function.

Kinin B1 receptor in adipocytes regulates glucose tolerance and predisposition to obesity.

Background: Kinins participate in the pathophysiology of obesity and type 2 diabetes by mechanisms which are not fully understood. Kinin B(1) receptor knockout mice (B(1) (-/-)) are leaner and exhibit improved insulin sensitivity.

Methodology/principal Findings: Here we show that kinin B(1) receptors in adipocytes play a role in controlling whole body insulin action and glucose homeostasis.

B1 and B2 kinin receptor participation in hyperproliferative and inflammatory skin processes in mice.

Background: Kinins are released during dermal injury and inflammation and seem to contribute to the pathogenesis of cutaneous diseases.

Objective: Participation of kinins in skin inflammatory process was evaluated using knockout mice and non-peptide kinin receptor antagonists.

Methods: Chronic skin inflammation was induced by multiple applications of TPA in mice ear.

Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E.

Kinin B1 receptor is involved in chronic inflammation and expressed in human atherosclerotic lesions. However, its significance for lesion development is unknown. Therefore, we investigated the effect of kinin B1 receptor deletion on the development of atherosclerosis and aortic aneurysms in apolipoprotein E-deficient (ApoE(-/-)) mice.

Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity.

Objective: Kinins mediate pathophysiological processes related to hypertension, pain, and inflammation through the activation of two G-protein-coupled receptors, named B(1) and B(2). Although these peptides have been related to glucose homeostasis, their effects on energy balance are still unknown.

Research Design And Methods: Using genetic and pharmacological strategies to abrogate the kinin B(1) receptor in different animal models of obesity, here we present evidence of a novel role for kinins in the regulation of satiety and adiposity.