Publications by authors named "Ranjini M Krishnan"

Current day concentrations of ambient air pollution have been associated with a range of adverse health effects, particularly mortality and morbidity due to cardiovascular and respiratory diseases. In this review, we summarize the evidence from epidemiological studies on long-term exposure to fine and coarse particles, nitrogen dioxide (NO2) and elemental carbon on mortality from all-causes, cardiovascular disease and respiratory disease. We also summarize the findings on potentially susceptible subgroups across studies.

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Background: Exposure to traffic-related air pollution (TRAP) is considered a trigger for acute cardiovascular events. Diesel Exhaust (DE) is a major contributor to TRAP in the world. We evaluated the effect of DE inhalation on circulating blood cell populations, hematological indices, and systemic inflammatory cytokines in humans using a specialized facility.

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Objectives: This study evaluated the association of long- and short-term air pollutant exposures with flow-mediated dilation (FMD) and baseline arterial diameter (BAD) of the brachial artery using ultrasound in a large multicity cohort.

Background: Exposures to ambient air pollution, especially long-term exposure to particulate matter <2.5 μm in aerodynamic diameter (PM(2.

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Article Synopsis
  • Exposure to diesel exhaust was found to significantly increase systolic blood pressure (BP) in young, nonsmoking participants during controlled studies.
  • Systolic BP measurements showed an increase of up to 4.4 mm Hg within 30 to 90 minutes after exposure, while heart rate and diastolic pressure remained unchanged.
  • The findings support previous observational studies linking traffic-related air pollution to cardiovascular risks and suggest potential public health implications due to widespread exposure.
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